Experiences in Surgical Management for 122 Cases of Primary Carcinoma of the Gallbladder_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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杨培 , 严律南 , 智星 , 李波

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原发性胆囊癌外科治疗

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目的探讨原发性胆囊癌治疗的措施。方法对我院1998年4月至2003年2月外科治疗的122例原发性胆囊癌患者的临床资料，结合部分患者随访结果进行分析总结。结果19例Ⅰ、Ⅱ及Ⅲ期胆囊癌患者手术治疗效果满意； 103例Ⅳ、Ⅴ期胆囊癌患者中34例行根治或扩大根治术，根治切除率为33.0%，余69例行姑息性手术治疗，行胆囊癌根治术后患者的平均生存时间明显长于姑息性手术者（17.6个月 vs 7.3个月）。结论对胆囊癌应采取积极的、个体化的治疗措施。扩大根治术可使部分Ⅳ、Ⅴ期胆囊癌患者受益。应注意淋巴结清扫的范围和做到无残留癌的根治性切除。对综合治疗的研究还需进一步深入。

Citation： 杨培,严律南,智星,李波. Experiences in Surgical Management for 122 Cases of Primary Carcinoma of the Gallbladder. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2004, 11(3): 253-254. doi: Copy

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1. Muratore A, Polastri R, Capussotti L. Radical surgery for gallbladder cancer: current options [Ｊ]. Eur J Surg Oncol, 2000; 26(5)∶438.
2. Suzuki K, Kimura T, Ogawa H. Is laparoscopic cholecystectomy hazardous for gallbladder cancer? [Ｊ]. Surgery, 1998; 123(3)∶311.
3. Z’graggen K, Birrer S, Maurer CA, et al. Incidence of port site recurrence after laparoscopic cholecystectomy for preoperatively unsuspected gallbladder carcinoma [Ｊ]. Surgery, 1998; 124(5)∶831.
4. Varshney S, Buttirini G, Gupta R. Incidental carcinoma of the gallbladder [Ｊ]. Eur J Surg Oncol, 2002; 28(1)∶4.
5. Shimada H, Endo I, Togo S, et al. The role of lymph node dissection in the treatment of gallbladder carcinoma [Ｊ]. Cancer, 1997; 79(5)∶892.
6. Kondo S, Nimura Y, Hayakawa N, et al. Regional and paraaortic lymphadenectomy in radical surgery for advanced gallbladder carcinoma [Ｊ]. Br J Surg, 2000; 87(4)∶418.
7. Oohashi Y, Shirai Y, Wakai T, et al. Adenosquamous carcinoma of the gallbladder warrants resection only if curative resection is feasible [Ｊ]. Cancer, 2002; 94(11)∶3000.
8. Kresl JJ, Schild SE, Henning GT, et al. Adjuvant external beam radiation therapy with concurrent chemotherapy in the management of gallbladder carcinoma [Ｊ]. Int J Radiat Oncol Biol Phys, 2002; 52(1)∶167.
9. 杜继东，李为民，许红兵，等. 经肝动脉插管化疗栓塞术治疗晚期胆囊癌肝转移32例 [Ｊ]. 世界华人消化杂志， 2000； 8（1）∶117.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Experiences in Surgical Management for 122 Cases of Primary Carcinoma of the Gallbladder

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