Clinical Study on pTNM Classification in Predicting Prognosis of Hepatic Cell Carcinoma after Liver Transplantation_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

LU Minqiang , CHEN Guihua , YANG Yang , CAI Changjie , HE Xiaoshun , ZHU Xiaofeng.

Transplantation Surgery, The First Affiliated Hospital of Zhongshan University, Guangzhou 510080, China;

Corresponding author：

Keywords：

Liver transplantation Hepatic cell carcinoma pTNM classification

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【Abstract】Objective To evaluate the value of pTNM classification in predicting the prognosis of hepatic cell carcinoma after liver transplantation.
Methods Fifty-nine HCC cases undergoing liver transplantation between April 1993 and January 2003 were retrospectively reviewed. Fiftynine cases were staged by using the pTNM classification.
Results The 1-year survival rates were 66.67%, 66.67%, 40.91% and 31.75% for Ⅰ，Ⅱ，Ⅲa and Ⅳa stages，2-year survival rates were 66.67%, 66.67%, 21.29% and 31.75%, the difference was not statistically significant.
Conclusion The pTNM classification is not good enough to predict the prognosis of hepatic cell carcinoma after liver transplantation.

Citation： LU Minqiang,CHEN Guihua,YANG Yang,CAI Changjie,HE Xiaoshun,ZHU Xiaofeng.. Clinical Study on pTNM Classification in Predicting Prognosis of Hepatic Cell Carcinoma after Liver Transplantation. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2004, 11(5): 393-395. doi: Copy

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1. International Union Against Cancer (UICC). TNM classification of malignant tumor [M]. 5ed. New York: WileyLiss, 1997∶477-477.
2. Mazzaferro V, Rondinara GF, Rossi G, et al. Milan multicenter experience in liver transplantation for hepatocellular carcinoma [J]. Transplant Proc, 1994; 26(6)∶3557.
3. Llovet JM, Bruix J, Fuster J, et al. Liver transplantation for small hepatocellular carcinoma: the tumornodemetastasis classification does not have prognostic power [J]. Hepatology, 1998; 27(6)∶1572.
4. Marsh JW, Dvorchik I, Bonham CA, et al. Is the pathologic TNM staging system for patients with hepatoma predictive of outcome? [J]. Cancer, 2000; 88(3)∶538.
5. Marsh JW, Dvorchik I, Iwatsuki S. Liver transplantation in the treatment of hepatocellular carcinoma [J]. J Hepatobiliary Pancreat Surg, 1998; 5(1)∶24.
6. Levy I, Sherman M. Staging of hepatocellular carcinoma: assessment of the CLIP, Okuda, and ChildPugh staging systems in a cohort of 257 patients in Toronto [J]. Gut, 2002; 50(6)∶881.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Clinical Study on pTNM Classification in Predicting Prognosis of Hepatic Cell Carcinoma after Liver Transplantation

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