Simultaneous PancreasKidney Transplantation: Indications and the Current Status_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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黄东胜 , 徐骁

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胰肾联合移植; 糖尿病

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近40年来，胰腺移植在基础和临床研究方面都获得了令人振奋的长足进步。据国际胰腺移植登记中心（IPTR）记录，全球已实施了18 900余例胰腺移植（截至2002年10月），其中绝大多数在美国（近14 000例），约90%为胰肾联合移植（SPK）。迄今为止，SPK被公认是治疗糖尿病合并肾功能衰竭的最有效的方法。据报道，胰腺移植受体1年生存率超过95%，3年生存率接近90%；移植胰腺有功能（患者不依赖胰岛素）者的1年和3年生存率分别为83%和77%。

Citation： 黄东胜,徐骁. Simultaneous PancreasKidney Transplantation: Indications and the Current Status. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2003, 10(6): 528-529. doi: Copy

1.	Gruessner AC, Sutherland DE. Analysis of United States (US) and nonUS pancreas transplants reported to the United network for organ sharing (UNOS) and the international pancreas transplant registry (IPTR) as of October 2001 [J]. Clin Transpl, 2001; 41.
2.	Kahl A, Bechstein WO, Frei U. Trends and perspectives in pancreas and simultaneous pancreas and kidney transplantation [J]. Curr Opin Urol, 2001; 11(2)∶165.
3.	Kelly WD, Lillehei RC, Merkel FK, et al. Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy [J].Surgery, 1967; 61(6)∶827.
4.	Sollinger HW, Odorico JS, Knechtle SJ, et al. Experience with 500 simultaneous pancreaskidney transplants [J]. Ann Surg, 1998; 228(3)∶284.
5.	Sutherland DE, Gruessner RW, Dunn DL, et al. Lessons learned from more than 1 000 pancreas transplants at a single institution [J]. Ann Surg, 2001; 233(4)∶463.
6.	Becker BN, Odorico JS, Becker YT, et al. Simultaneous pancreaskidney and pancreas transplantation [J]. J Am Soc Nephrol, 2001; 12(11)∶2517.

1. Gruessner AC, Sutherland DE. Analysis of United States (US) and nonUS pancreas transplants reported to the United network for organ sharing (UNOS) and the international pancreas transplant registry (IPTR) as of October 2001 [J]. Clin Transpl, 2001; 41.
2. Kahl A, Bechstein WO, Frei U. Trends and perspectives in pancreas and simultaneous pancreas and kidney transplantation [J]. Curr Opin Urol, 2001; 11(2)∶165.
3. Kelly WD, Lillehei RC, Merkel FK, et al. Allotransplantation of the pancreas and duodenum along with the kidney in diabetic nephropathy [J].Surgery, 1967; 61(6)∶827.
4. Sollinger HW, Odorico JS, Knechtle SJ, et al. Experience with 500 simultaneous pancreaskidney transplants [J]. Ann Surg, 1998; 228(3)∶284.
5. Sutherland DE, Gruessner RW, Dunn DL, et al. Lessons learned from more than 1 000 pancreas transplants at a single institution [J]. Ann Surg, 2001; 233(4)∶463.
6. Becker BN, Odorico JS, Becker YT, et al. Simultaneous pancreaskidney and pancreas transplantation [J]. J Am Soc Nephrol, 2001; 12(11)∶2517.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Simultaneous PancreasKidney Transplantation: Indications and the Current Status

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