ObjectiveTo investigate the correlation between perioperative blood transfusion and hepatic postoperative infection. MethodsOne hundred and thirty patients undergoing hepatic operation were analyzed retrospectively on the relation of perioperative blood transfusion with postoperative infective morbidity and mortality in the period 1989-1999. The patients were divided into blood transfused group and nontransfused group. The major or minor hepatectomy was performed in 53 patients with hepatic malignancy and benign diseases. ResultsIn the blood transfused group, the infective morbidity and perioperative mortality rate was 38.5% and 16.7% respectively, significantly higher than those in nontransfused group (11.5% and 3.8% respectively), P＜0.05. The total lymphocyte count was lower in transfused group than that in nontransfused group. The postoperative antibiotics used time and length of hospital stay were (9.7±4.2) days and (18.7±13.1) days respectively in transfused group than those in nontransfused group (5.3±2.3) days and (12.7±5.2) days respectively. ConclusionThe results suggest that hepatic postoperative infective morbidity and mortality are related with perioperative blood transfusion. Any strategy to reduce blood loss in liver surgery and decrease blood transfusion would be helpful to lower postoperative infective morbidity.
Citation：
PU Qingfan,YAN Lnan,SUN Suikang,ZHANG Chuanrong,CAO Gaojian,DAI Huawei,CHEN Zhanwei,LI Rongxiang. Correlation Between Perioperative Blood Transfusion and Hepatic Postoperative Infection. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2003, 10(2): 144-146. doi:
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| 1. |
Johnson M, Mannar R, Wu AV. Correlation between blood loss and inferior vena caval pressure during liver resection [J]. Br J Surg, 1998; 85(2)∶188.
|
| 2. |
Opelz G, Graver B, Terasaki PI. Induction of high kidney survival rate by multiple transfusion [J]. Lancet, 1981; 1（8232）∶1223.
|
| 3. |
李荫山，朱善德，杜晓炬，等. 全肝血流阻断无血切肝技术的临床应用 [J].中国普外基础与临床杂志， 1999； 6（4）∶243.
|
| 4. |
严律南. 体外静脉转流下的肝叶切除术 [J].中国普外基础与临床杂志，1999； 6（4）∶238.
|
| 5. |
Huguet C, Gallot D, Offenstadt G. Letter: Normothermic complete hepatic vascular exclusion for extensive resection of the liver [J]. N Engl J Med， 1976; 294(1)∶51.
|
| 6. |
Huguet C, Gavelli A, Chieco PA, et al. Liver ischemia for hepatic resection: where is the limit? [J]. Surgery, 1992; 111(3)∶251.
|
| 7. |
Nagasue N, Hayashi T, Uchida M. Techniques of hepatectomy for hepatocellular carcinoma [J]. Dig Surg, 1995; 12(1)∶34.
|
| 8. |
严律南，曾勇，林琦远，等. 半肝血流阻断下肝能量代谢变化的研究 [J].中华肝胆外科杂志，2000； 6（1）∶10.
|
| 9. |
严律南. 肝门板及其在肝胆外科的应用 [J]. 中国普外基础与临床杂志，1998； 5（4）∶239.
|
| 10. |
Jones RM,Moulton CE,Hardy KJ.Central venous pressure and its effect on blood loss during liver resection [J].Br J Surg, 1998; 85(5)∶1058.
|
- 1. Johnson M, Mannar R, Wu AV. Correlation between blood loss and inferior vena caval pressure during liver resection [J]. Br J Surg, 1998; 85(2)∶188.
- 2. Opelz G, Graver B, Terasaki PI. Induction of high kidney survival rate by multiple transfusion [J]. Lancet, 1981; 1（8232）∶1223.
- 3. 李荫山，朱善德，杜晓炬，等. 全肝血流阻断无血切肝技术的临床应用 [J].中国普外基础与临床杂志， 1999； 6（4）∶243.
- 4. 严律南. 体外静脉转流下的肝叶切除术 [J].中国普外基础与临床杂志，1999； 6（4）∶238.
- 5. Huguet C, Gallot D, Offenstadt G. Letter: Normothermic complete hepatic vascular exclusion for extensive resection of the liver [J]. N Engl J Med， 1976; 294(1)∶51.
- 6. Huguet C, Gavelli A, Chieco PA, et al. Liver ischemia for hepatic resection: where is the limit? [J]. Surgery, 1992; 111(3)∶251.
- 7. Nagasue N, Hayashi T, Uchida M. Techniques of hepatectomy for hepatocellular carcinoma [J]. Dig Surg, 1995; 12(1)∶34.
- 8. 严律南，曾勇，林琦远，等. 半肝血流阻断下肝能量代谢变化的研究 [J].中华肝胆外科杂志，2000； 6（1）∶10.
- 9. 严律南. 肝门板及其在肝胆外科的应用 [J]. 中国普外基础与临床杂志，1998； 5（4）∶239.
- 10. Jones RM,Moulton CE,Hardy KJ.Central venous pressure and its effect on blood loss during liver resection [J].Br J Surg, 1998; 85(5)∶1058.
