凡是涉及一个脏器基本结构的研究，不论是大体的、显微镜的、分子的、基因水平或功能状态的研究，都属于临床外科中的基础研究范畴。解剖学研究虽然是外科临床基础研究中最古老的项目，但是随着新科技和临床外科学的发展，又从未间断地添加新的研究内容。例如当前的可视化人体的研究便是个突出的例子。肝、胆管血循环的研究在当代的胆道外科学和移植外科学中占有重要的位置, 而上世纪50年代初期的肝内管道解剖学研究，奠定了现代肝脏外科的基础。
Citation： 黄志强. Angiological Studies and the Progress of Hepatobiliary Surgery. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2003, 10(3): 186-190. doi: Copy
| 1. | McNulty JG.ed. Radiology of the liver [M]. 1st ed. Philadelphia, W.B.： Saunders CO, 1977∶8-17. |
| 2. | Hiatt JR, Gabbay J, Busuttil RW. Surgical anatomy of the hepatic arteries in 1 000 cases [J]. Ann Surg, 1994; 220(1)∶50. |
| 3. | Neuhaus P, Blumhardt G, Bechstein WO, et al.Technique and results of bil;iary reconstruction using sidetoside choledochojejunostomy in 300 orthotopic liver transplants [J]. Ann Surg, 1994; 219(4)∶426. |
| 4. | Huang ZQ, Huang XQ. Changing patterns of traumatic bile duct injuries: a review of forty years experience [J]. World J Gastroenterol, 2002; 8(1)∶5. |
| 5. | Stapleton GN, Hickman R, Terblanche J. Blood supply of the right and left hepatic ducts [J]. Br J Surg, 1998; 85(2)∶202. |
| 6. | Schlitt HJ, Meier PN, Nashan B, et al. Reconstructive surgery for ischemictype lesions at the bile duct bifurcation after liver transplantation [J]. Ann Surg, 1999; 229(1)∶137. |
| 7. | Koffron A, Ferrario M, Parsons W, et al.Failed primary management of iatrogenic biliary: Incidence and significance of concomitant hepatic arterial disruption [J]. Surgery, 2001; 130(4)∶722. |
| 8. | Compagno J, Grisham JW. Scanning electron microscopy of extrahepatic biliary obstruction [J]. Arch Pathol, 1974; 97(6)∶348. |
| 9. | Northover JM, Williams ED, Terblanche J.The investigation of small vessel anatomy by scanning electron microscopy of resin casts [J]. J Anat, 1980; 130(1)∶43. |
| 10. | Terblanche J, Allison HF, Northover JM. An ischemic basis for biliary strictures [J]. Surgery, 1983; 94(1)∶52. |
| 11. | Lautt WW. ed. Hepatic circulation in health and disease [M]. 1st ed. N.Y.： Raven Press, 1981∶92-101. |
| 12. | Haratake J, Hisaoka M, Yamamoto O,et al. Morphological changes of hepatic microcirculation in experimental rat cirrhosis: a scanning electron microscopic study [J]. Hepatology, 1991; 13(5)∶ 952. |
| 13. | Ohtani O. The peribiliary portal system in the rabbit liver [J]. Arch Histol Jap, 1979; 42(2)∶153. |
| 14. | Schemmer P, Enomoto N, Bradford BU, et al. Autonomic nervous system and gutderived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation [J]. World J Surg, 2001; 25(4)∶399. |
| 15. | 陈永亮，黄志强，黄洁，等.大鼠肝门部整块切除术后门静脉动脉化重建肝血流的实验模型 [J]. 中华普通外科杂志，2001; 16(2)∶94. |
| 16. | 陈永亮，黄晓强，黄志强，等.门静脉动脉化对实验性梗阻性黄疸大鼠肝脏微血管的影响 [J]. 中华外科杂志，2001; 39(9)∶713. |
| 17. | 陈永亮，黄志强，王迎宾，等.门静脉动脉化对实验性梗阻性黄疸大鼠肝细胞调亡的影响 [J]. 中华普通外科杂志，2000; 15(6)∶348. |
| 18. | 陈永亮，黄志强，王迎宾，等. 门静脉动脉化对实验性梗阻性黄疸大鼠肝脏再生的影响 [J]. 解放军医学杂志，2001; 26(10)∶740. |
| 19. | 陈永亮，黄晓强，黄志强，等.门静脉动脉化时梗阻性黄疸大鼠肝脏血管铸型的变化 [J]. 军医进修学院学报，2001; 22(4)∶262. |
| 20. | Ozawa K, Takeda H, Yamaoka Y, et al. Adenine nucleotide metabolism in regenerative, atrophic, and necrotizing processes of the liver [J]. Gastroenterology, 1974; 67(6)∶1225. |
| 21. | Nonami T, Asahi K, Harada A, et al. Effect of hyperdynamic circulatory support on hepatic hemodynamics, oxygen supply and demand after massive hepatectomy [J]. Surgery, 1991; 109(3 Pt 1)∶277. |
| 22. | Yoshioka S, Miyazaki M, Shimizu H, et al. Hepatic venous hemoglobin oxygen saturation predicts regenerative status of remnant liver after partial hepatectomy in rats [J]. Hepatology, 1998; 27（5）∶1349. |
| 23. | Shimizu Y, Miyazaki H, Shimizu H, et al. Beneficial effects of arterialization of the portal vein on extended hepatectomy [J]. Br J Surg, 2000; 87(6)∶784. |
| 24. | Muller V, Ott R, Tannapfel A, et al. Arterialization of the portal vein in liver transplantation:a new microsurgical model in the rat [J]. Transplantation, 2001; 71(7)∶977. |
| 25. | Haratake J, Hisaoka M, Furuta A, et al. A scanning electron microscopic study of postnatal development of rat peribiliary plexus [J]. Hepatology, 1991; 14(6)∶1196. |
| 26. | Yamamoto T,Kobayashi T,Philips MJ.Perinodular arteriolar plexus in liver cirrhosis.Scanning electron microscopy of microvascular casts [J]. Liver, 1984; 4(1)∶50. |
| 27. | Habib N, Houssin D, Carol C, et al. Experimental reduction of portal hypertension by mechanical increase of liver portal flow [J]. Lancet, 1991; 337(8732)∶16. |
| 28. | Jiao LR, Seifalian AM, Davidson BR, et al. In vivo evaluation of an implantable portal pump system for augmenting liver perfusion [J]. Br J Surg, 2000; 87(8)∶1024. |
| 29. | Jiao LR, Seifalian AM, Mathie RT, et al. Portal flow augmentation for liver cirrhosis [J]. Br J Surg, 2000; 87(8)∶984. |
| 30. | Kinoshita H, Sakai K, Hirohashi K, et al. Preoperative portal vein embolization for hepatocellular carcinoma [J]. World J Surg, 1986; 10(5)∶803. |
| 31. | Makuuchi M, Thai BL, Takayasu K, et al. Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report [J]. Surgery, 1990; 107(5)∶521. |
| 32. | Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained with dynamic CT [J]. Radiology, 1993; 188(2)∶405. |
| 33. | Wakabayashi H, Nakano S, Ishimura K, et al. Changes in arterial and portal perfusion in embolized and nonembolized hepatic lobes after portal vein embolization evaluated by helical computed tomography [J]. Surgery Today, 2001; 31(11)∶991. |
| 34. | Sugawara Y, Yamamoto J, Higashi H, et al. Preoperative portal embolization in patients with hepatocellular carcinoma [J]. World J Surg, 2002; 26(1)∶105. |
| 35. | Elias D, De Baere T, Roche A, et al. During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma [J]. Br J Surg, 1999; 86(6)∶784. |
| 36. | Slooter GD, Marquet RL, Jeekel J, et al. Tumor growth stimulation after partial hepatectomy can be reduced by treatment with tumor necrosis factor alpha [J]. Br J Surg, 1995; 82(1)∶129. |
| 37. | Picardo A, Karpoff HM, Lee Ng B, et al. Partial hepatectomy accelerates local tumor growth: potential roles of local cytokine activation [J]. Surgery, 1998; 124(1)∶57. |
| 38. | 黄晓强，杨可祯，黄志强，等. 阻断胆管后肝微循环改变的实验研究 [J]. 中华实验外科杂志，1987; 4(4)∶151. |
| 39. | 黄晓强，黄志强，杨可祯，等.肝内胆管结石肝脏微血管改变的观察 [J]. 中华外科杂志，1987; 25(6)∶330. |
| 40. | Kock NG, Hahnloser P, Roding B, et al. Interaction between portal venous and hepatic arterial blood flow: an experimental study in the dog [J]. Surgery, 1972; 72（3）∶414. |
| 41. | Lenthall J, Reynolds TB, Donovan AJ. Excessive output of bile in chronic hepatic disease [J]. Surg Gynecol Obstet, 1970; 130(2)∶243. |
| 42. | Dumont AE. Significance of excess drainage of bile in patients with chronic hepatic disease [J]. Surg Gynecol Obstet, 1982; 154(2)∶209. |
| 43. | Kono N, Nakanuma Y. Ultrastructural and immunohistochemical studies of the intrahepatic peribiliary capillary plexus in normal livers and extrahepatic biliary obstruction in human beings [J]. Hepatology, 1992; 15(3)∶411. |
| 44. | Strazzabosco M, Spirli C, Okolicsanyi L. Pathophysiology of the intrahepatic biliary epithelium [J]. J Gastroenterol Hepatol, 2000; 15(3)∶244. |
| 45. | Bosch J, Enriquez R, Groszmann RJ, et al. Chronic bile duct ligation in the dog: Hemodynamic characterization of a portal hypertensive model [J]. Hepatology, 1983; 3(6)∶1002. |
| 46. | Mathie RT, Nagorney DM, Lewis MH, et al. Hepatic hemodynamics after chronic obstruction of the biliary tract in the dog [J]. Surg Gynecol Obstet, 1988; 166(2)∶125. |
- 1. McNulty JG.ed. Radiology of the liver [M]. 1st ed. Philadelphia, W.B.： Saunders CO, 1977∶8-17.
- 2. Hiatt JR, Gabbay J, Busuttil RW. Surgical anatomy of the hepatic arteries in 1 000 cases [J]. Ann Surg, 1994; 220(1)∶50.
- 3. Neuhaus P, Blumhardt G, Bechstein WO, et al.Technique and results of bil;iary reconstruction using sidetoside choledochojejunostomy in 300 orthotopic liver transplants [J]. Ann Surg, 1994; 219(4)∶426.
- 4. Huang ZQ, Huang XQ. Changing patterns of traumatic bile duct injuries: a review of forty years experience [J]. World J Gastroenterol, 2002; 8(1)∶5.
- 5. Stapleton GN, Hickman R, Terblanche J. Blood supply of the right and left hepatic ducts [J]. Br J Surg, 1998; 85(2)∶202.
- 6. Schlitt HJ, Meier PN, Nashan B, et al. Reconstructive surgery for ischemictype lesions at the bile duct bifurcation after liver transplantation [J]. Ann Surg, 1999; 229(1)∶137.
- 7. Koffron A, Ferrario M, Parsons W, et al.Failed primary management of iatrogenic biliary: Incidence and significance of concomitant hepatic arterial disruption [J]. Surgery, 2001; 130(4)∶722.
- 8. Compagno J, Grisham JW. Scanning electron microscopy of extrahepatic biliary obstruction [J]. Arch Pathol, 1974; 97(6)∶348.
- 9. Northover JM, Williams ED, Terblanche J.The investigation of small vessel anatomy by scanning electron microscopy of resin casts [J]. J Anat, 1980; 130(1)∶43.
- 10. Terblanche J, Allison HF, Northover JM. An ischemic basis for biliary strictures [J]. Surgery, 1983; 94(1)∶52.
- 11. Lautt WW. ed. Hepatic circulation in health and disease [M]. 1st ed. N.Y.： Raven Press, 1981∶92-101.
- 12. Haratake J, Hisaoka M, Yamamoto O,et al. Morphological changes of hepatic microcirculation in experimental rat cirrhosis: a scanning electron microscopic study [J]. Hepatology, 1991; 13(5)∶ 952.
- 13. Ohtani O. The peribiliary portal system in the rabbit liver [J]. Arch Histol Jap, 1979; 42(2)∶153.
- 14. Schemmer P, Enomoto N, Bradford BU, et al. Autonomic nervous system and gutderived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation [J]. World J Surg, 2001; 25(4)∶399.
- 15. 陈永亮，黄志强，黄洁，等.大鼠肝门部整块切除术后门静脉动脉化重建肝血流的实验模型 [J]. 中华普通外科杂志，2001; 16(2)∶94.
- 16. 陈永亮，黄晓强，黄志强，等.门静脉动脉化对实验性梗阻性黄疸大鼠肝脏微血管的影响 [J]. 中华外科杂志，2001; 39(9)∶713.
- 17. 陈永亮，黄志强，王迎宾，等.门静脉动脉化对实验性梗阻性黄疸大鼠肝细胞调亡的影响 [J]. 中华普通外科杂志，2000; 15(6)∶348.
- 18. 陈永亮，黄志强，王迎宾，等. 门静脉动脉化对实验性梗阻性黄疸大鼠肝脏再生的影响 [J]. 解放军医学杂志，2001; 26(10)∶740.
- 19. 陈永亮，黄晓强，黄志强，等.门静脉动脉化时梗阻性黄疸大鼠肝脏血管铸型的变化 [J]. 军医进修学院学报，2001; 22(4)∶262.
- 20. Ozawa K, Takeda H, Yamaoka Y, et al. Adenine nucleotide metabolism in regenerative, atrophic, and necrotizing processes of the liver [J]. Gastroenterology, 1974; 67(6)∶1225.
- 21. Nonami T, Asahi K, Harada A, et al. Effect of hyperdynamic circulatory support on hepatic hemodynamics, oxygen supply and demand after massive hepatectomy [J]. Surgery, 1991; 109(3 Pt 1)∶277.
- 22. Yoshioka S, Miyazaki M, Shimizu H, et al. Hepatic venous hemoglobin oxygen saturation predicts regenerative status of remnant liver after partial hepatectomy in rats [J]. Hepatology, 1998; 27（5）∶1349.
- 23. Shimizu Y, Miyazaki H, Shimizu H, et al. Beneficial effects of arterialization of the portal vein on extended hepatectomy [J]. Br J Surg, 2000; 87(6)∶784.
- 24. Muller V, Ott R, Tannapfel A, et al. Arterialization of the portal vein in liver transplantation:a new microsurgical model in the rat [J]. Transplantation, 2001; 71(7)∶977.
- 25. Haratake J, Hisaoka M, Furuta A, et al. A scanning electron microscopic study of postnatal development of rat peribiliary plexus [J]. Hepatology, 1991; 14(6)∶1196.
- 26. Yamamoto T,Kobayashi T,Philips MJ.Perinodular arteriolar plexus in liver cirrhosis.Scanning electron microscopy of microvascular casts [J]. Liver, 1984; 4(1)∶50.
- 27. Habib N, Houssin D, Carol C, et al. Experimental reduction of portal hypertension by mechanical increase of liver portal flow [J]. Lancet, 1991; 337(8732)∶16.
- 28. Jiao LR, Seifalian AM, Davidson BR, et al. In vivo evaluation of an implantable portal pump system for augmenting liver perfusion [J]. Br J Surg, 2000; 87(8)∶1024.
- 29. Jiao LR, Seifalian AM, Mathie RT, et al. Portal flow augmentation for liver cirrhosis [J]. Br J Surg, 2000; 87(8)∶984.
- 30. Kinoshita H, Sakai K, Hirohashi K, et al. Preoperative portal vein embolization for hepatocellular carcinoma [J]. World J Surg, 1986; 10(5)∶803.
- 31. Makuuchi M, Thai BL, Takayasu K, et al. Preoperative portal embolization to increase safety of major hepatectomy for hilar bile duct carcinoma: a preliminary report [J]. Surgery, 1990; 107(5)∶521.
- 32. Miles KA, Hayball MP, Dixon AK. Functional images of hepatic perfusion obtained with dynamic CT [J]. Radiology, 1993; 188(2)∶405.
- 33. Wakabayashi H, Nakano S, Ishimura K, et al. Changes in arterial and portal perfusion in embolized and nonembolized hepatic lobes after portal vein embolization evaluated by helical computed tomography [J]. Surgery Today, 2001; 31(11)∶991.
- 34. Sugawara Y, Yamamoto J, Higashi H, et al. Preoperative portal embolization in patients with hepatocellular carcinoma [J]. World J Surg, 2002; 26(1)∶105.
- 35. Elias D, De Baere T, Roche A, et al. During liver regeneration following right portal embolization the growth rate of liver metastases is more rapid than that of the liver parenchyma [J]. Br J Surg, 1999; 86(6)∶784.
- 36. Slooter GD, Marquet RL, Jeekel J, et al. Tumor growth stimulation after partial hepatectomy can be reduced by treatment with tumor necrosis factor alpha [J]. Br J Surg, 1995; 82(1)∶129.
- 37. Picardo A, Karpoff HM, Lee Ng B, et al. Partial hepatectomy accelerates local tumor growth: potential roles of local cytokine activation [J]. Surgery, 1998; 124(1)∶57.
- 38. 黄晓强，杨可祯，黄志强，等. 阻断胆管后肝微循环改变的实验研究 [J]. 中华实验外科杂志，1987; 4(4)∶151.
- 39. 黄晓强，黄志强，杨可祯，等.肝内胆管结石肝脏微血管改变的观察 [J]. 中华外科杂志，1987; 25(6)∶330.
- 40. Kock NG, Hahnloser P, Roding B, et al. Interaction between portal venous and hepatic arterial blood flow: an experimental study in the dog [J]. Surgery, 1972; 72（3）∶414.
- 41. Lenthall J, Reynolds TB, Donovan AJ. Excessive output of bile in chronic hepatic disease [J]. Surg Gynecol Obstet, 1970; 130(2)∶243.
- 42. Dumont AE. Significance of excess drainage of bile in patients with chronic hepatic disease [J]. Surg Gynecol Obstet, 1982; 154(2)∶209.
- 43. Kono N, Nakanuma Y. Ultrastructural and immunohistochemical studies of the intrahepatic peribiliary capillary plexus in normal livers and extrahepatic biliary obstruction in human beings [J]. Hepatology, 1992; 15(3)∶411.
- 44. Strazzabosco M, Spirli C, Okolicsanyi L. Pathophysiology of the intrahepatic biliary epithelium [J]. J Gastroenterol Hepatol, 2000; 15(3)∶244.
- 45. Bosch J, Enriquez R, Groszmann RJ, et al. Chronic bile duct ligation in the dog: Hemodynamic characterization of a portal hypertensive model [J]. Hepatology, 1983; 3(6)∶1002.
- 46. Mathie RT, Nagorney DM, Lewis MH, et al. Hepatic hemodynamics after chronic obstruction of the biliary tract in the dog [J]. Surg Gynecol Obstet, 1988; 166(2)∶125.