ObjectiveTo evaluate and summarize the perioperative management experience of living related liver transplantation (LRLT). MethodsA retrospective analysis was made in perioperative management of 13 cases undergoing LRLT (15 times operation, including 2 cases of liver retransplantation) in our department from January 2001 to December 2002. ResultsAll the operations were successful. All the 13 donors were followed up regularly, 12 donors were uneventfully recovered after operation and 1 donor suffered from bile leakage due to T tube. The survival rate of recipients, who achieved longterm survival at 2 months to 2 years, was 92.3%(12/13); the survival rate of graft was 86.7%(13/15). One adult recipient with Wilson’s disease died of serious rejection on the 72nd day postoperatively. Two cases suffered from embolism of hepatic artery, one case received reduced size cadaveric liver retransplantation, the other case received liver retransplantation from cadaver, and they both achieved longterm survival after retransplantation. The other complications included: 1 case of serious rejection, 2 cases of ARDS, 6 cases of infection of microbe, 7 cases of serious hydrothorax, 1 cases of leakage of biliary tract, and so on. ConclusionPerfect preoperative management, which composes one of the key parts of LRLT, is critically important for both donor and recipient.
Citation：
LI Guoqiang,WANG Xuehao,LI Xiangcheng,ZHANG Feng,QIAN Jianmin,KONG Lianbao,ZHANG Hao,CHENG Feng,SUN Beicheng. The Perioperative Management of Living Donor Liver Transplantation. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2003, 10(4): 336-339. doi:
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Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
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- 2. 王学浩,杜竞辉,张峰,等.活体供肝原位部分肝移植一例报告 [J]. 中华器官移植杂志, 1995； 16(3)∶133.
- 3. 李国强,王学浩.活体肝移植临床研究的新进展 [J]. 中国普外基础与临床杂志, 2002； 9(4)∶279.
- 4. 王学浩,张峰,李相成,等.活体部分肝移植12例次临床报告 [J]. 中华医学杂志, 2002； 82(7)∶19.
- 5. 王学浩,李国强,李相成,等.活体肝移植手术经验回顾 [J]. 中国实用外科杂志, 2002； 22(6)∶89.
- 6. 王学浩,张峰,李相成,等.五例活体肝移植供体术后随访报告 [J]. 江苏医药, 2001； 27(10)∶729.
- 7. Renz JF, Roberts JP. Longterm complications of living donor liver transplantation [J]. Liver Transpl， 2000； 6（6 Suppl 2)∶S73.
- 8. Grewal HP, Thistlewaite JR Jr, Loss GE, et al. Complications in 100 livingliver donors [J]. Ann Surg, 1998； 228(2)∶214.
- 9. Ikegami T, Kawasaki S, Hashikura Y, et al. An alternative method of arterial reconstruction after hepatic arterial thrombosis following livingrelated liver transplantation [J]. Transplantation,2000； 69(9)∶1953.
- 10. Hashikura Y, Kawasaki S, Terada M,et al. Longterm results of livingrelated donor liver graft transplantation: a singlecenter analysis of 110 transplants [J]. Transplantation, 2001； 72(1)∶95.
- 11. Tojimbara T, Fuchinoue S, Nakajima I, et al. Factors affecting survival after livingrelated liver transplantation [J]. Transpl Int， 2000； 13(Suppl 1)∶S136.
