Objective To investigate the clinical choice on graft size and the type of donor’s hepatectomy in adult living related partial liver transplantation. Methods The literatures in recent years on the donor’s evaluation, the size of liver grafts, the types of donor hepatectomy and safety of donor in adult living related partial liver transplantation were reviewed.Results The size of liver graft is a crucial factor related to the safety of donor and the prognosis of the recipient. GW/ESLW≥30%, GW/BW≥0.8% may be the lowest limits. Left lobe contained middle hepatic vein, extended left lobe with leftside caudle lobe, right lobe or extended right lobe contained middle hepatic vein may be the practical choice.Conclusion It is important to make a reasonable choice of liver graft according to the estimation of GW/ESLW or GW/BW, and the anatomy of liver in adult living related partial liver transplantation.
Citation： YAO Huihua,WEN Tianfu,YAN Lnan. Clinical Decision for Adult Living Related Partial Liver Transplantation. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2003, 10(4): 411-414. doi: Copy
| 1. | Seaberg EC, Belle SH, Beriger KC, et al. Liver transplantation in the United States from 1987-1998: Updated results from the PittUNOS liver transplant registry. In: Cecka JM, Teraski PI, eds. Clinical transplants 1998 [M]. Los Angeles: UCLA Typing Laboratory, 1999∶17-37. |
| 2. | Bravata DM, Olkin I, Barnato AE, et al. Healthrelated quality of life after liver transplantation: a metaanalysis [J]. Liver Transpl Surg, 1999; 5(4)∶318. |
| 3. | Harper AM, Rosendale JD. The UNOS open waiting list and donor registry. In: Cecka JM, Terasaki PI, eds. Clinical Transplants 1997 [M]. UCLA Typing Laboratory, 1998∶61-80. |
| 4. | Raia S, Nery JR, Mies S. Liver transplantation from live donors [J]. Lancet, 1989: 2(8661)∶497. |
| 5. | Hashikura Y, Kawasaki S, Terada M, et al. Longterm results of livingrelated donor liver graft transplantation: a singlecenter analysis of 110 transplants [J]. Transplantation, 2001; 72(1)∶95. |
| 6. | Haberal M, Buyukpamukcu N, Telatar H, et al. Segmental living liver transplantation in children and adults [J]. Transplant Proc, 1992; 24(6)∶2687. |
| 7. | Hashikura Y, Makuuchi M, Kawasaki S, et al. Successful livingrelated partial liver transplantation to an adult patient [J]. Lancet, 1994; 343(8907)∶1233. |
| 8. | Lo CM, Gertsch, Fan ST. Living unrelated liver transplantation between spouses for fulminant hepatic failure [J]. Br J Surg, 1995； 82(8)∶1037. |
| 9. | Sugawara Y, Makuuchi M, Takayama T, et al. Smallforsize grafts in livingrelated liver transplantation [J]. J Am Coll Surg, 2001; 192(4)∶510. |
| 10. | Renz JF, Busutti RW. Adulttoadult living donor liver transplantation a critical analysis [J]. Seminar in liver disease. 2000; 20(4)∶411. |
| 11. | Higashiyama H, Yamaguchi T, Mori K, et al. Graft size assessment by preoperative computed tomography in living related partial liver transplantation [J]. Br J Surg, 1993; 80(4)∶489. |
| 12. | Cheng YF, Chen CL, Huang TL, et al.Single imaging modality resonance imaging [J]. Transplantation, 2001; 72(9)∶1527. |
| 13. | Urata K, Kawasaki S, Matsunami H, et al.Calculation of child and adult standard liver volume for liver transplantation [J]. Hepatology, 1995; 21(5)∶1317. |
| 14. | Kawaski S, Makuuchi M, Ishizone S, et al. Liver regeneration in recipients and donors after transplantation [J]. Lancet, 1992; 339(8793)∶580. |
| 15. | Stone HH, Long WD, Smith RB 3rd, et al. Physiological considerations in major hepatic resections [J]. Am J Surg, 1969; 117(1)∶78. |
| 16. | Emond JC, Renz JF, Ferrell LD, et al. Functional analysis of grafts from living donors: implications for the treatment of older recipients [J]. Ann Surg, 1996; 224(4)∶544. |
| 17. | Lo CM, Fan ST, Liu CL, et al. Minimum graft size for successful living donor liver transplantation [J]. Transplantation, 1999; 68(8)∶1112. |
| 18. | BenHain M, Emre S, Facciuto M, et al. Critical graft size in adulttoadult living donor liver transplantation, the impact of the recipient disease [J]. Liver Transpl, 2001; 7(11)∶948. |
| 19. | Fan ST, Lo CM, Liu CL, et al. Safety of donors in liver donor liver transplantation using right lobe grafts [J]. Arch Surg, 2000; 135(3)∶336. |
| 20. | Kiuchi T, Kasahara M, Uryuhara K, et al. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors [J]. Transplantation, 1999; 67(2)∶ 321. |
| 21. | Hiatt JR, Gabby J, Busuttil RW. Surgical anatomy of the hepatic arteries in 1000 cases [J]. Ann Surg, 1994; 220(1)∶50. |
| 22. | Bismuth H. Surgical anatomy and anatomical surgery of the liver [J]. World J Surg, 1982; 6(1)∶3. |
| 23. | Marcos A, Fisher RA, Ham JM, et al. Liver regeneration and function in donor and recipient after right lobe adult living donor liver transplantation [J]. Transplantation, 2000; 69(7)∶1375. |
| 24. | Reichert PR, Renz JF, D’Albuquerque LA, et al. Surgical anatomy of the left lateral segment as applied to livingdonor and splitliver transplantation： a clinicopathologic study [J]. Ann Surg, 2000; 232(5)∶658. |
| 25. | Miyagawa S, Hashikura Y, Miwa S, et al. Concomitant caudate lobe resection as an option for donor hepatectomy in adult living related liver transplantation [J]. Transplantation, 1998; 66(5)∶661. |
| 26. | Takayama T, Makuuchi M, Kubota K, et al.Livingrelated transplantation of left liver plus caudate lobe [J]. J Am Coll Surg, 2000; 190(5)∶635. |
| 27. | Kawasaki S, Hashikura Y, Ikegami T, et al. Indications and needs for livingrelated transplantation in adults [J]. J Gastroenterol Hepatol, 2000; 15(Suppl)∶E175. |
| 28. | Yamaoka Y, Washida M, Honda K, et al.Liver transplantation using a right lobe graft from a living related donor [J]. Transplantation, 1994; 57(7)∶1127. |
| 29. | Lo CM, Fan ST, Liu CL, et al. Adulttoadult living donor transplantation using extended right lobe grafts [J]. Ann Surg, 1997; 226(3)∶261. |
| 30. | Marcos A, Fisher RA, Han JM, et al.Right lobe living donor liver transplantation [J]. Transplantation, 1999; 68(6)∶798. |
| 31. | Sakamoto S, Uemoto S, Uryuhara K, et al. Graft size assessment and analysis of donors for living donor liver transplantation using right lobe [J]. Transplantation, 2001; 71(10)∶1407. |
| 32. | Villa VH, Chen CL, Chen YS, et al. Right lobe living donor liver grafting addressing the middle hepatic vein controversy [J]. Am J Transplant, 2001; 1(2)∶261. |
| 33. | Fan ST, Lo CM, Liu CL. Technical refinement in adulttoadult living donor liver transplantation using right lobe graft [J]. Ann Surg, 2000; 231(1)∶126. |
| 34. | Sugawara Y, Makuuchi M, Takayama T, et al. Right lateral sector graft in adult livingrelated liver transplantation [J]. Transplantation, 2002; 73(1)∶111. |
| 35. | Sadan DL. Current status of partial liver transplantation in adults from cadaveric and living donors. In: Willis C, Maddery , Eugene R, eds. Transplantation of liver[M]. third ed. Philadephia: Sorrell. Lippincott Williams & Wilkin, 2001∶65-78. |
| 36. | Broelsch CE, Malago M, Testa G, et al. Living donor liver transplantation in adults: outcome in Europe [J]. Liver Transpl, 2000; 6(6 Suppl 2)∶S64. |
| 37. | Fair JH, Johnson MW, Gerber DA. Adulttoadult living donor liver transplantation using right lobe: Single center experience [J]. Am J Transplant, 2001; 1(2)∶316. |
| 38. | Malago M, Rogiers X, Burdelski M, et al. Living related liver transplantation: 36 cases at the University of Hamberg [J]. Transplant Proc, 1994; 26(6)∶3620. |
- 1. Seaberg EC, Belle SH, Beriger KC, et al. Liver transplantation in the United States from 1987-1998: Updated results from the PittUNOS liver transplant registry. In: Cecka JM, Teraski PI, eds. Clinical transplants 1998 [M]. Los Angeles: UCLA Typing Laboratory, 1999∶17-37.
- 2. Bravata DM, Olkin I, Barnato AE, et al. Healthrelated quality of life after liver transplantation: a metaanalysis [J]. Liver Transpl Surg, 1999; 5(4)∶318.
- 3. Harper AM, Rosendale JD. The UNOS open waiting list and donor registry. In: Cecka JM, Terasaki PI, eds. Clinical Transplants 1997 [M]. UCLA Typing Laboratory, 1998∶61-80.
- 4. Raia S, Nery JR, Mies S. Liver transplantation from live donors [J]. Lancet, 1989: 2(8661)∶497.
- 5. Hashikura Y, Kawasaki S, Terada M, et al. Longterm results of livingrelated donor liver graft transplantation: a singlecenter analysis of 110 transplants [J]. Transplantation, 2001; 72(1)∶95.
- 6. Haberal M, Buyukpamukcu N, Telatar H, et al. Segmental living liver transplantation in children and adults [J]. Transplant Proc, 1992; 24(6)∶2687.
- 7. Hashikura Y, Makuuchi M, Kawasaki S, et al. Successful livingrelated partial liver transplantation to an adult patient [J]. Lancet, 1994; 343(8907)∶1233.
- 8. Lo CM, Gertsch, Fan ST. Living unrelated liver transplantation between spouses for fulminant hepatic failure [J]. Br J Surg, 1995； 82(8)∶1037.
- 9. Sugawara Y, Makuuchi M, Takayama T, et al. Smallforsize grafts in livingrelated liver transplantation [J]. J Am Coll Surg, 2001; 192(4)∶510.
- 10. Renz JF, Busutti RW. Adulttoadult living donor liver transplantation a critical analysis [J]. Seminar in liver disease. 2000; 20(4)∶411.
- 11. Higashiyama H, Yamaguchi T, Mori K, et al. Graft size assessment by preoperative computed tomography in living related partial liver transplantation [J]. Br J Surg, 1993; 80(4)∶489.
- 12. Cheng YF, Chen CL, Huang TL, et al.Single imaging modality resonance imaging [J]. Transplantation, 2001; 72(9)∶1527.
- 13. Urata K, Kawasaki S, Matsunami H, et al.Calculation of child and adult standard liver volume for liver transplantation [J]. Hepatology, 1995; 21(5)∶1317.
- 14. Kawaski S, Makuuchi M, Ishizone S, et al. Liver regeneration in recipients and donors after transplantation [J]. Lancet, 1992; 339(8793)∶580.
- 15. Stone HH, Long WD, Smith RB 3rd, et al. Physiological considerations in major hepatic resections [J]. Am J Surg, 1969; 117(1)∶78.
- 16. Emond JC, Renz JF, Ferrell LD, et al. Functional analysis of grafts from living donors: implications for the treatment of older recipients [J]. Ann Surg, 1996; 224(4)∶544.
- 17. Lo CM, Fan ST, Liu CL, et al. Minimum graft size for successful living donor liver transplantation [J]. Transplantation, 1999; 68(8)∶1112.
- 18. BenHain M, Emre S, Facciuto M, et al. Critical graft size in adulttoadult living donor liver transplantation, the impact of the recipient disease [J]. Liver Transpl, 2001; 7(11)∶948.
- 19. Fan ST, Lo CM, Liu CL, et al. Safety of donors in liver donor liver transplantation using right lobe grafts [J]. Arch Surg, 2000; 135(3)∶336.
- 20. Kiuchi T, Kasahara M, Uryuhara K, et al. Impact of graft size mismatching on graft prognosis in liver transplantation from living donors [J]. Transplantation, 1999; 67(2)∶ 321.
- 21. Hiatt JR, Gabby J, Busuttil RW. Surgical anatomy of the hepatic arteries in 1000 cases [J]. Ann Surg, 1994; 220(1)∶50.
- 22. Bismuth H. Surgical anatomy and anatomical surgery of the liver [J]. World J Surg, 1982; 6(1)∶3.
- 23. Marcos A, Fisher RA, Ham JM, et al. Liver regeneration and function in donor and recipient after right lobe adult living donor liver transplantation [J]. Transplantation, 2000; 69(7)∶1375.
- 24. Reichert PR, Renz JF, D’Albuquerque LA, et al. Surgical anatomy of the left lateral segment as applied to livingdonor and splitliver transplantation： a clinicopathologic study [J]. Ann Surg, 2000; 232(5)∶658.
- 25. Miyagawa S, Hashikura Y, Miwa S, et al. Concomitant caudate lobe resection as an option for donor hepatectomy in adult living related liver transplantation [J]. Transplantation, 1998; 66(5)∶661.
- 26. Takayama T, Makuuchi M, Kubota K, et al.Livingrelated transplantation of left liver plus caudate lobe [J]. J Am Coll Surg, 2000; 190(5)∶635.
- 27. Kawasaki S, Hashikura Y, Ikegami T, et al. Indications and needs for livingrelated transplantation in adults [J]. J Gastroenterol Hepatol, 2000; 15(Suppl)∶E175.
- 28. Yamaoka Y, Washida M, Honda K, et al.Liver transplantation using a right lobe graft from a living related donor [J]. Transplantation, 1994; 57(7)∶1127.
- 29. Lo CM, Fan ST, Liu CL, et al. Adulttoadult living donor transplantation using extended right lobe grafts [J]. Ann Surg, 1997; 226(3)∶261.
- 30. Marcos A, Fisher RA, Han JM, et al.Right lobe living donor liver transplantation [J]. Transplantation, 1999; 68(6)∶798.
- 31. Sakamoto S, Uemoto S, Uryuhara K, et al. Graft size assessment and analysis of donors for living donor liver transplantation using right lobe [J]. Transplantation, 2001; 71(10)∶1407.
- 32. Villa VH, Chen CL, Chen YS, et al. Right lobe living donor liver grafting addressing the middle hepatic vein controversy [J]. Am J Transplant, 2001; 1(2)∶261.
- 33. Fan ST, Lo CM, Liu CL. Technical refinement in adulttoadult living donor liver transplantation using right lobe graft [J]. Ann Surg, 2000; 231(1)∶126.
- 34. Sugawara Y, Makuuchi M, Takayama T, et al. Right lateral sector graft in adult livingrelated liver transplantation [J]. Transplantation, 2002; 73(1)∶111.
- 35. Sadan DL. Current status of partial liver transplantation in adults from cadaveric and living donors. In: Willis C, Maddery , Eugene R, eds. Transplantation of liver[M]. third ed. Philadephia: Sorrell. Lippincott Williams & Wilkin, 2001∶65-78.
- 36. Broelsch CE, Malago M, Testa G, et al. Living donor liver transplantation in adults: outcome in Europe [J]. Liver Transpl, 2000; 6(6 Suppl 2)∶S64.
- 37. Fair JH, Johnson MW, Gerber DA. Adulttoadult living donor liver transplantation using right lobe: Single center experience [J]. Am J Transplant, 2001; 1(2)∶316.
- 38. Malago M, Rogiers X, Burdelski M, et al. Living related liver transplantation: 36 cases at the University of Hamberg [J]. Transplant Proc, 1994; 26(6)∶3620.