PREVENTION AND TREATMENT OF SURGICAL SITE INFECTION_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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杨春明

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外科手术部位; 外科感染

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每位外科医师均会遭遇到外科感染，这是手术技术自身所决定了的，外科手术必然破坏人体宿主抵抗力的第一道防线皮肤和粘膜屏障，使得细菌得以进入体内。从外科发展历史看，因外科感染而死亡是很常见的，特别是在19世纪末叶以前，当时截肢术死亡率在25%~90%之间，美国内战时期则为50%左右，这主要是外源性感染所致。但从现代外科学观点看，外科感染的内涵已发生了许多重要变化，如医院内获得性感染超过了患者原有的感染；体内的内源性正常菌群感染多于外源性致病细菌感染；外科手术后的手术部位感染（surgical site infection，SSI）多于需要外科处理的一般化脓性感染。其中SSI已成为值得关注的临床课题。

Citation： 杨春明. PREVENTION AND TREATMENT OF SURGICAL SITE INFECTION. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(1): 4-5. doi: Copy

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1. Dunn DL. Infection. In: Greenfield LJ, Malholland MW, Oldham KT, et al. ed. Surgery: Scientific Principles and Practice [M]. 2nd ed. Philadelphia: LippincottRaven,1997∶159-181.
2. Sands K, Vineyard G, Platt R. Surgical site infections occurring after hospital discharge [Ｊ]. J Infect Dis, 1996; 173(4)∶963.
3. Gurevich I. Surgical site infections: simplifying the definitions [Ｊ]. Infect Control Hosp Epidemiol, 1995; 16(6)∶669.
4. Dunn DL. Diagnosis and treatment of infection. In: Norton JA, Bollinger RR, Chang AB, et al. ed. Surgery: Basic Science and Clinic Evidence [M]. New York: Springer, 2001∶193-220.
5. Anonymous.National nasocomial infections surveilance (NNIS) system report,data summery from October 1986-April 1998,issued June 1998 [Ｊ].Am J Infect Control, 1998; 26(5)∶522.
6. Howard RJ.Surgical infection.In: Schwartz SI,Shires GT,Spencer FC, et al.ed.Principles of Surgery.7th ed [M]. New York: McGrawHill, 1999∶123-139.
7. Gorecki P, Schein M, Rucinski JC. Antibiotic administration in patients undergoing common surgical procedures in a community teaching hospital: the chaos continues [Ｊ]. World J Surg, 1999; 23(4)∶433.
8. Anonymous. Antimicrobial prophylaxis in surgery [Ｊ]. Med Lett, 1995; 37(1)∶79.
9. Meier DE, Nkor SK, Aasa DA, et al. Prospective randomized comparision of two preoperative skin preparation techniques in a developing world country [Ｊ]. World J Surg, 2001; 25(4)∶441.
10. Osman MO, Jensen SL. Surgical gloves: current problems [Ｊ]. World J Surg, 1999; 23(6)∶630.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

PREVENTION AND TREATMENT OF SURGICAL SITE INFECTION

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