HUANG Chengliang , LIU Houdong.
  • Department of General Surgery, The Hospital of Lasha Tibet Area Military Command of PLA, Lasha 850003;
Inducing differenation Gastric neoplasms T-lymphocyte subsets Interleukin-2 receptor All transretinoic acid
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Objective  To evaluate the effect of inducing differenation of all trans retinoic acid (ATRA) on immunologic function of patients with gastric cancer.
Methods  T-lymphocyte subsets(T-Ls) and interleukin-2 receptor(sIL-2R) of 56 patients with gastric cancer after treatment of ATRA were studied.
Results  In radical gastric cancer resection group, the serum CD3,CD4 and CD4/CD8 rate were higher and sIL-2R were lower than those in the control group, after treatment of ATRA, CD3,CD4 and CD4/CD8 rate and sIL2R were as high as those in the control group. In the non-operative or palliative gastric resection group, CD3,CD4 and CD4/CD8 rates were increased markedly and the serum sIL-2R was decreased significantly than those in the control group.
Conclusion  ATRA inducing differenation can improve the immunity of the patients with gastric cancer.

Citation： HUANG Chengliang,LIU Houdong.. EFFECT OF INDUCING DIFFERENATION OF ALL TRANS RETINOIC ACID ON IMMUNITY OF PATIENTS WITH GASTRIC CARCINOMA. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2001, 8(3): 166-168. doi: Copy