• Department of General Surgery, The Affiliated Hospital, Luoyang Medical College, Luoyang 471003;
Liver Salvia mitiorrhizare Ischemia-reperfusion injury
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Objective  To study the efect of IH764-3 on ischemia-reperfusion (I/R) injury in rat liver.
Methods  Rats were divided into 3 groups, the control group was not subjected to ischemia and no treatment was given. I/R injury group was subjected to 40 minutes ischemia followed by reperfusion for 120 minutes. The IH7643 group (40mg/kg) was administred at ischemia and reperfusion.
Results  In the IH764-3 group, sereum levels of ALT, AST, AKP and γ-GT were significantly lower than those in the I/R group. Energy charge level recovery was significantly higher with IH7643 (P＜0.05), hepatic ultrastructure was better preserved with IH764-3.
Conclusion  IH764-3 may be useful in the treatment of hepatic ischemia reperfusion injury

Citation： LIU Jinbiao,LIU Xianli,ZHANG Shouxi,et al.. PROTECTIVE EFFECT OF SALVIA MILTIORRHIZAE ON ISCHEMIA-REPERFUSION INJURY IN RAT LIVER. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2001, 8(4): 227-229. doi: Copy