To evaluate the effect of intraperitoneal hyperthermo-chemotherapy (IPHC) on immunologic function of patients with gastrointestinal malignant tumor (GMT). The authors determined the serum T-lymphocyte subsets (T-LS) and interleukin-2 receptor (sIL-2R) of 32 patients with GMT after IPHC, and compared the two indexes with 20 healthy control group. Results: Before IPHC the serum CD＋3, CD＋4, CD＋8 and CD＋4/CD＋8 were higher and sIL-2R were lower than control group, after IPHC, CD＋3, CD＋4, CD＋8 and CD＋4/CD＋8 increased obviously (Ｐ＜0.01) and the serum sIL-2R decreased significantly (Ｐ＜0.01). Conclusion: The IPHC can improve the patients immunologic function.
Citation：
Ran Jianghua,Zhang Jiahua,Guo Qun,et al.. EFFECT OF INTRAPERITONEAL HYPERTHERMO-CHEMOTHERAPY ON T-LYMPHOCYTE SUBSETS AND sIL2R LEVEL IN PATIENTS WITH GASTROINTESTINAL MALIGNANCY TUMOR. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1999, 6(3): 156-157. doi:
Copy
Copyright © the editorial department of CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY of West China Medical Publisher. All rights reserved
| 1. |
陈军， 林言箴， 尹治然. 进展期胃肠道恶性肿瘤术后早期腹腔内化疗. 癌症， 1994； 13(3)∶271.
|
| 2. |
孙念绪， 蔡志民. 进展期大肠癌术后早期腹腔灌洗化疗. 中华肿瘤杂志， 1998； 20(3)∶222.
|
| 3. |
Taradi M, Urano M, Taradi SK, et al. Augmentation of mouse natural killer cell activity by combined hyperthermi and streptococcul preparation, OK432 (Picibanil) treatment. Int J Hyperthermia, 1991; 7(4)∶653.
|
| 4. |
王娟， 宋志杰， 刘怀深等. 胃癌术前卡铂腹腔化疗肿瘤组织浓度测定及药物动力学研究. 中国肿瘤临床， 1998； 25(4)∶261.
|
| 5. |
李求是. 肿瘤患者手术前后T细胞亚群细胞毒性细胞因子及血浆抑制因子变化. 中国免疫学杂志， 1992； 8(4)∶247.
|
| 6. |
Lotze MT, Finn OJ. Recent advances in cellular immunology: inplications for immunity to cancer. Immunol Today, 1990; 11(6)∶190.
|
| 7. |
Laurencea A, Rucin MD, David L, et al. The soluble interleukin2 receptor biology, function and clinical application. Ann Intern Med, 1990; 113(8)∶619.
|
| 8. |
陈垦， 汤斌， 官成浓等. 胃癌病人血清sIL2R水平与红细胞免疫功能的相关性研究. 实用癌症杂志， 1996； 11(2)∶98.
|
- 1. 陈军， 林言箴， 尹治然. 进展期胃肠道恶性肿瘤术后早期腹腔内化疗. 癌症， 1994； 13(3)∶271.
- 2. 孙念绪， 蔡志民. 进展期大肠癌术后早期腹腔灌洗化疗. 中华肿瘤杂志， 1998； 20(3)∶222.
- 3. Taradi M, Urano M, Taradi SK, et al. Augmentation of mouse natural killer cell activity by combined hyperthermi and streptococcul preparation, OK432 (Picibanil) treatment. Int J Hyperthermia, 1991; 7(4)∶653.
- 4. 王娟， 宋志杰， 刘怀深等. 胃癌术前卡铂腹腔化疗肿瘤组织浓度测定及药物动力学研究. 中国肿瘤临床， 1998； 25(4)∶261.
- 5. 李求是. 肿瘤患者手术前后T细胞亚群细胞毒性细胞因子及血浆抑制因子变化. 中国免疫学杂志， 1992； 8(4)∶247.
- 6. Lotze MT, Finn OJ. Recent advances in cellular immunology: inplications for immunity to cancer. Immunol Today, 1990; 11(6)∶190.
- 7. Laurencea A, Rucin MD, David L, et al. The soluble interleukin2 receptor biology, function and clinical application. Ann Intern Med, 1990; 113(8)∶619.
- 8. 陈垦， 汤斌， 官成浓等. 胃癌病人血清sIL2R水平与红细胞免疫功能的相关性研究. 实用癌症杂志， 1996； 11(2)∶98.
