Diagnosis and surgical procedures were studied in this paper. Twentyfive cases of insulinoma were treated surgically from 1970 to 1997, in which 10 patients had Whipple′s triad so that the early diagnosis could be made. The sites of tumours were found in 10 out of 12 undergoing. Selective celiac angiongraphy with the accuracy rate of 83%, but B-ultrasonography and CT gave only 10% (4 out of 25) and 40%(8 out of 20) respectively. In this series, 5 cases underwent bodytail pancreatectomy and 20 cases enucleation of insulinoma. Blood glucose levels were tested during operation in 15 cases, and they all reached the normal level one hour after the tumours were completely removed. The authors consider that Whipple′s triad is the main basis in diagnosis of insulinoma. The selective celiac angiongraphy play an important role in detecting and locating the tumour. If diagnosis is made, surgical operation should be taken. The blood glucose monitoring during operation is the hallmark for complete resection of insulinomas.
Citation：
Gao Peng,Wang Zhenge,Zhou Yanzhen.. DIAGNOSIS AND TREATMENT OF INSULINOMA (ANALYSIS OF 25 CASES). CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1999, 6(6): 357-358. doi:
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- 1. 沈钰如. 不伴警告症状的低血糖发作的临床意义. 国外医学内分泌学分册， 1994； 3(2)∶138.
- 2. 石美鑫， 熊汝成， 李鸿儒等主编. 实用外科学. 第1版. 北京： 人民卫生出版社， 1992； 812～814.
- 3. Stefanini P. Surgical treatment and prognosis of insulinoma. Clin gastroenterol, 1974; 3(4)∶697.
- 4. 曾宪九. 110例胰岛素瘤的诊断和外科治疗经验. 中华外科杂志， 1987； 25(3)∶129.
- 5. 谭毓铨主编. 现代肝胆胰腺外科. 第1版. 长春： 吉林科学技术出版社， 1992∶243～245.
- 6. Pietrabissa A, Chimi SM, Vander VG, et al. Localization of insulinoma by laparoscopic infragastric inspection of the pancreas and contact ultrasonography. Surg Oncol, 1993; 2(1)∶83.
- 7. Doppman JL, Chang R, Fraker DL. Localization of insulinoma to regions of the pancreas by intraarterial stumulation with calcium. Ann Inter Med, 1995; 123(4)∶269.
- 8. Van Heerden JA, Grant CS, Czako PF, et al. Occult functioning insulinomas: which localizing studies are indicated? Surg, 1992; 112(6)∶1010.
- 9. 张静霞， 张金榜， 王强. 胰岛细胞瘤手术前后的处理. 普外临床， 1990； 5(1)∶20.
