CLINICAL STUDY ON THE CHANGES OF HEPATIC MACROPHAGE FUNCTION IN PATIENTS WITH OBSTRUCTIVE JAUNDICE_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical College, Chongqing 400038;

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Keywords：

Obstructive jaundice; Kupffer cell; Endotoxemia

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Kupffer cell phagocytic function and plasma endotoxin level in 36 patients with obstructive jaundice were observed. The results indicated that kupffer cell phagocytic function was inhibited and the plasma endotoxemia level was markedly increased as compared with those in the control group Ｐ＜0.05 and Ｐ＜0.01 respectively. Kupffer cell phagocytic function were recoverd and plasma endotoxemia alleviated while the biliary obstruction was released by surgery.

Citation： Li Zhihua,Han Benli,He Zhengping,et al.. CLINICAL STUDY ON THE CHANGES OF HEPATIC MACROPHAGE FUNCTION IN PATIENTS WITH OBSTRUCTIVE JAUNDICE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1998, 5(2): 95-96. doi: Copy

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1. Dixon JM. Factors affecting morbidity and mortality after surgery for obstructive jaundice: a review of 373 patients. Gut, 1983; 24(9)∶845.
2. Armstrong CP, Dixon Jm, Taylor TV. Surgical experience of deeply jaundiced patients with bile duct obstruction. Br J Surg, 1984; 71(3)∶234.
3. Clements WD, Halliday MI, Mccaigue MD. Effects of extrahepatic obstructive jaundice on kupffer cell clearance capacity. Arch Surg, 1993; 128(2)∶200; discussion 204.
4. Pain JA, Bailey ME. Measurement of operative palsma endotoxin levels in jaundiced and nonjaundiced patients. Eur Surg Res, 1987; 19(4)∶207.
5. Allison EM, Prentice CR, Kennedy AC. Renal function and other factor in obstructive jaundice. Br J Surg, 1979; 66(6)∶392.
6. Fox ES, Peter PM, Selwyn AI. Clearance of gutderived endotoxing by the liver: releasenal modification of 3H 14Clipopolysaccharide by isolated rat kupffer cells. Gastroenterology, 1989; 96(2)∶456.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

CLINICAL STUDY ON THE CHANGES OF HEPATIC MACROPHAGE FUNCTION IN PATIENTS WITH OBSTRUCTIVE JAUNDICE

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