RELATIONSHIPOFP62CmycPROTEINEXPRESSIONTOESTROGENPROGESTERONERECEPTORSINBREASTCANCERANDITSCLINICALSIGNIFICANCE_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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DepartmentofGeneralSurgery,FirstAffiliatedHospital,WestChinaUniversityofMedicalSciences,Chengdu610041;

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Keywords：

Breastneoplasm; P62Cmycprotein; Estrogenreceptor; Progesteronereceptor

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InordertounderstandtherelationshipofP62CmycproteinexpressiontoERandPRinbreastcanceranditsclinicalsignificance,weexaminedexpressionofP62Cmycproteinin107breastcarcinomasbyusingimmunohistochemicaltechniques(LSAB).TheresultsshowedthatthepositiverateofP62Cmycproteinexpressionwas63.55%(68/107).TheoverexpressionofP62Cmycproteinrelatednegativelywithsurvival.94.00%ofthecaseswithoverexpressionofP62Cmycproteinsurvived≤5years,65.00%survived gt;5years lt;10yearsand21.62%survived≥10years.ThereweresignificantassociationsofP62Cmycproteinexpressionwithadvancedclinicalstage,highhistologicalgrade,andpositiveaxillarynodestatusinbreastcancer,butnorelationshipbetweenhormonereceptorsandP62Cmyc.AllofthesefindingssuggestthatoverexpressionofP62Cmycproteinmightbeanimportantprognosticfactor,andthedetectionofP62Cmycproteinmightbearrangedasaregularpathologicalexaminationinthecasesofbreastcancer.

Citation： YangJinqiao,ZhouLeilei,LiangCuiping,etal.. RELATIONSHIPOFP62CmycPROTEINEXPRESSIONTOESTROGENPROGESTERONERECEPTORSINBREASTCANCERANDITSCLINICALSIGNIFICANCE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1998, 5(5): 270-271. doi: Copy

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CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

RELATIONSHIPOFP62CmycPROTEINEXPRESSIONTOESTROGENPROGESTERONERECEPTORSINBREASTCANCERANDITSCLINICALSIGNIFICANCE

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