Since 1995, 8 patients with unresectable carcinoma of pancreatic body and tail has been treated by regional chemotherapy. 5-Fu and MMC were administered through a subcutaneous placed drug pump connecting to the splenic artery catheler. Twelve patients with unresectable pancreatic carcinoma being treated by peripheral venous chemotherapy were as control. The results showed that median survival time with regional chemotherapy with drug pump group as 7.0 months, and the time of peripheral venous chemotherapy group as 4.2 months. The difference between them was significant. This therapy was effective to prolong survival time of patients with unresectable pancreatic carcinoma.
Citation:
Ji Zongzheng,Chen Xi,Ma Shuangyu,et al.. CLINICAL APPLICATION OF REGIONAL CHEMOTHERAPY WITH SUBCUTANEOUS PLACED DRUG PUMP FOR UNRESECTABLE CARCINOMA OF PANCREATIC BODY AND TAIL. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1998, 5(6): 343-344. doi:
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Ozaki H, Kinoshita T, Kosage T,et al. Anaggerssive therapeutic approach to carcinoma of the body and tail of the pancreas. Cancer, 1996; 77(11)∶2240.
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- 1. Richard AB. Cancer of the pancreas: the value of radical and palliative surgery. Ann Surg, 1973; 177∶325.
- 2. Matusuno S. Surgical treatment for carcinoma of the pancreas. Am J Surg, 1986; 152∶499.
- 3. Raben A, Mychaizak B, Brennan MF, et al.Feasibility study of the treatment of primary unresectable carcinoma of pancread with 103Pd brachytherapy. Int J Radiat Oncol Boil Phys, 1996; 35(2)∶351.
- 4. Ozaki H, Kinoshita T, Kosage T,et al. Anaggerssive therapeutic approach to carcinoma of the body and tail of the pancreas. Cancer, 1996; 77(11)∶2240.