EFFECT OF TUMOR NECROSIS FACTOR ON ACUTE NECROTIZING PANCREATITIS OF MONKEYS AND THERAPEUTIC EFFECT OF STILAMIN_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

Yang Zhi ¹ , Yang Zhiying ² , Tang Weisong ² , et al. ²

Department of General Surgery, Affiliated Hospital of Chengde Medical College, Chengde 067000;

Corresponding author：

Keywords：

Monkey; Tumor necrosis factor; Acute necrotizing pancreatitis; Stilamin

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

In the early stage of acute necrotizing pancreatitis (ANP) of experimental monkeys, the concentration of tumor necrosis factor (TNF) in blood was significantly increased. Stilamin could significantly reduce the level of TNF, decrease the mortality, and prolong the survival time of monkeys. The authors draw the conclusion that TNF is an important inflammatory media in the early stage of ANP. Stilamin can significantly inhibit the inflammatory process and has good effect in the treatment of ANP in experimental monkeys.

Citation： Yang Zhi,Yang Zhiying,Tang Weisong,et al.. EFFECT OF TUMOR NECROSIS FACTOR ON ACUTE NECROTIZING PANCREATITIS OF MONKEYS AND THERAPEUTIC EFFECT OF STILAMIN. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1996, 3(1): 4-6. doi: Copy

1.	Gerami A.Inflamatory cytokines.Clinical Immunopath,1992;62:S3.
2.	Camussi G,Albano E,Tetta C,et al.The molecular action of tumor necrosis factor α.Eur J Biochem,1991;202:3.
3.	赵平,杨植,唐伟松等.腹腔液淀粉酶测定在估价急性胰腺炎病变程度及预后的作用.第二届全国普外基础与临床研讨会资料会编.1995:76.
4.	Pohlman TH.An endothelial cell surface factor induced in vitro by lipopolysaccharide.Interleukin 1 and tumor necrosis factor increases neutrophils adherence by a WB 18-dependent mechanism.J Immunol,1986;136:4548.
5.	Choi TK,Mok F,Zhan WH,et al.Somatostatin in the treatment of acute pancreatitis:a prospective randomized controlled trial.Gut,1989;30:223.
6.	Buchler MW,Binder M,Friess H.Role of somatostatin and its analogues in the treatment of acute and chronic pancreatitis.Gut,1994;35(Suppl 3):S15.

1. Gerami A.Inflamatory cytokines.Clinical Immunopath,1992;62:S3.
2. Camussi G,Albano E,Tetta C,et al.The molecular action of tumor necrosis factor α.Eur J Biochem,1991;202:3.
3. 赵平,杨植,唐伟松等.腹腔液淀粉酶测定在估价急性胰腺炎病变程度及预后的作用.第二届全国普外基础与临床研讨会资料会编.1995:76.
4. Pohlman TH.An endothelial cell surface factor induced in vitro by lipopolysaccharide.Interleukin 1 and tumor necrosis factor increases neutrophils adherence by a WB 18-dependent mechanism.J Immunol,1986;136:4548.
5. Choi TK,Mok F,Zhan WH,et al.Somatostatin in the treatment of acute pancreatitis:a prospective randomized controlled trial.Gut,1989;30:223.
6. Buchler MW,Binder M,Friess H.Role of somatostatin and its analogues in the treatment of acute and chronic pancreatitis.Gut,1994;35(Suppl 3):S15.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

EFFECT OF TUMOR NECROSIS FACTOR ON ACUTE NECROTIZING PANCREATITIS OF MONKEYS AND THERAPEUTIC EFFECT OF STILAMIN

Abstract Full text Figures/Tables Video References Cited by

Format

Content