A simple model of canine auto-trasplantation of liver was set up by ourselves, and the effects of hepatic artery ischemia (HAI) on ultrastructure of liver and biliary duct transplanted were observed. The results showed that the liver and biliary cells swelled slightly, mitochondrial matrix was loose and ridges were vague just often perfusion. Afte HAI for 3 hours the edema of hepatic and biliary cells aggravated cytoplasm was loose, mitochondria enlarged and partly vacuolar degenerated, ridges broke or disappeared, flocculent focal densites was seen in the matrix, endoplasmic retculum distended obviously, and the ribosome depolymerizated. So we consider that HAI causes obvious damage to hepatic and biliary cells. These indicate that HAI is one of the important factors of complication after liver transplantation, especially some biliary complications.
Citation:
Li Yiming,Yang Wenbin,Ji Zongzheng,et al.. EFFECTS OF HEPATIC ARTERY ISCHEMIA ON ULTRASTRUCTURE OF LIVER AND BILIARY DUCT IN CANINE AUTO-TRANSPLANATION. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1995, 2(4): 196-197Z转封四. doi:
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黎一鸣,康业安,秦兆寅.犬肝原位自体移植模型的建立及意义.中华实验外科杂志,1995;12(2):113.
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Jnerins RL, Parrchild RB. The role of transplantation in cwer disease. Surg Clin North Am, 1989;69(2):371.
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Stevens LH, Bmond JC, Piper JB, et al. Hepaic artery thrombosis in Infants. Transplantation, 1992;53(2);396.
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Li yingming, Jenrins RL, Lewis WD. The premery observation and approach to effects of schernic time of hepaic, artery on the results of caer transplantation. Journal of XIAN Medical Univesity, 1993;5:81.
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- 1. Starzl TE, Demetris AJ, Live transplantation; A31-year perspective Par I. Carr Probl Surg, 1990;27(2):114.
- 2. 黎一鸣,康业安,秦兆寅.犬肝原位自体移植模型的建立及意义.中华实验外科杂志,1995;12(2):113.
- 3. Jnerins RL, Parrchild RB. The role of transplantation in cwer disease. Surg Clin North Am, 1989;69(2):371.
- 4. Stevens LH, Bmond JC, Piper JB, et al. Hepaic artery thrombosis in Infants. Transplantation, 1992;53(2);396.
- 5. Li yingming, Jenrins RL, Lewis WD. The premery observation and approach to effects of schernic time of hepaic, artery on the results of caer transplantation. Journal of XIAN Medical Univesity, 1993;5:81.