Progress of Non-Invasive Arterial Measurements and Evaulation of Cardiovascular Injury of OSAHS_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

WANG Yan , ZHANG Xiujuan , LI Qingyun

Department of Respiratory Medicine，Ruijin Hospital，Shanghai jiaotong University.Shanghai 200025,China;

Corresponding author：

Keywords：

动脉; 无创检测技术; 阻塞性睡眠呼吸暂停低通气综合征; 心血管损伤; ; 评估

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阻塞性睡眠呼吸暂停低通气综合征( OSAHS) 是心血管疾病的独立危险因素[1,2 ]。睡眠过程中反复发生氧饱和度降低和频繁觉醒是心血管损伤的病理生理基础。OSAHS 血管损害的早期改变可表现为血管僵硬度增加, 对亚临床血管病变患者开展早期动脉弹性功能检测及早进行干预, 可有效预防心血管疾病的发生。本文就常用的无创动脉硬化检测 lt;br / gt;技术及其对OSAHS 心血管损伤的评估相关研究进展进行综述。

Citation： WANG Yan,ZHANG Xiujuan,LI Qingyun. Progress of Non-Invasive Arterial Measurements and Evaulation of Cardiovascular Injury of OSAHS. Chinese Journal of Respiratory and Critical Care Medicine, 2010, 9(3): 329-331. doi: Copy

1.	Lorenzi-Filho G，Drager LF.Obstructive sleep apnea and atherosclerosis：a new paradigm.Am J Respir Crit Care Med，2007，175：1219-1221.
2.	王菡侨，何权瀛.阻塞性睡眠呼吸暂停综合征与高血压.中国呼吸与危重监护杂志，2008，7：313-317.
3.	O’Leary DH，Polak JF，Kronmal RA，et al.Carotidartery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults.N Engl J Med，1999，340：34-42.
4.	Takiuchi S，Kamide K，Miwa Y，et al.Diagnostic value of carotid intima-media thickness and plaque score for predicting target organ damage in patients with essential hypertension.J Hum Hypertens，2004，18：17-23.
5.	宝辉，苗懿德，张颖.老年人血尿酸水平与颈动脉粥样硬化程度的相关性研究.中华全科医师杂志，2005，4：13-16.
6.	万里凯，王小燕，张琴，等.年轻人颈动脉内中膜厚度与血压及QT离散度的相关性研究.中华超声影像学杂志，2008，17：858-860.
7.	刘俊，姚欢.高血压病患者颈动脉内膜中层厚度与静息心率的关系.医师进修杂志，2005，28：39-42.
8.	李振光，伍期专，唐朝枢，等.动脉粥样硬化患者颈动脉内膜中层厚度与血浆溶血磷脂酸含量的变化.中华医学杂志，2004，84：1071-1072.
9.	匡鼎伟，丁峰，薛骏，等.维持性血透患者颈动脉内膜中层厚度增厚及其影响因素分析.中华肾脏病杂志，2005，21：577-581.
10.	王云开，魏云峰，王梦洪，等.颈动脉内膜中层增厚患者血清基质金属蛋白酶-9、可溶性P-选择素和高敏C-反应蛋白变化的研究.中国综合临床，2008，24：1241-1243.
11.	Kiykim AA，Camsari A，Kahraman S，et al.Increased incidence of carotid artery wall changes and associated variables in hemodialysis patients without symptomatic cardiovascular disease.Yousei Med J，2004，45：247-254.
12.	王新，张磊，饶小胖，等.颈动脉内膜中层厚度影响因素的研究进展.国外医学内分泌学分册，2004，24：423-424.
13.	World Health Organization.International society of hypertension guidelines for the management of hypertension.Guidelines Subcommittee.J Hypertens，1999，17：151-183.
14.	Hopkins KD，Lehmann ED，Gosling RG.Aortic compliance measurements：a non-invasive indicator of atherosclerosis? Lancet，1994，343：1447.
15.	Filipovský J，Tichá M，Cífková R，et al.Large artery stiffness and pulse wave reflection：results of a population-based study.Blood Press，2005，14：45-52.
16.	Laurent S，Boutouyrie P，Asmar R，et al.Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.Hypertension，2001，37：1236-1241.
17.	Blacher J，Guerin AP，Pannier B，et al.Impact of aortic stiffness on survival in end stage renal disease.Circulation，1999，99：2434-2439.
18.	Cruickshank K，Riste L，Anderson SG，et al.Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance：an integrated index of vascular function? Circulation，2002，106：2085-2090.
19.	Vaitkevicius PV，Fleg JL，Engel JH，et al.Effects of age and aerobic capacity on arterial stiffness in healthy adults.Circulation，1993，88：1456-1462.
20.	Lehmann ED，Watts GF，Gosling RG.Aortic distensibility and hypercholesterolemia.Lancet，1992，340：1171-1172.
21.	Lehmann ED，Gosling RG，Sonksen PH.Arterial wall compliance in diabetes.Diabet Med，1992，9：114-119.
22.	Rajkumar C，Kingwell BA，Cameron JD，et al.Hormonal therapy increases arterial compliance in postmenopausal women.J Am Coll Cardiol，1997，30：350-356.
23.	孙卫平，吴永全，李觉，等.脉搏波传导速度与冠心病心功能不全的相关性.中华内科杂志，2008，47：382-384.
24.	Okura T，Watanabe S，Kurata M，et al.Relationship between cardio-ankle vascular index （CAVI） and carotid atherosclerosis in patients with essential hypertension.Hypertens Res，2007，30：335-340.
25.	Satoh N，Shimatsu A，Kato Y，et al.Evaluation of the cardio-ankle Index，a new indicator of arterial stiffness independent of blood pressure，in obesity and metabolic syndrome.Hypertense Res，2008，31：1921-1930.
26.	Takenaka T，Hoshi H，Kato N，et al.Cardioankle vascular index to screen cardiovascular diseases in patients with end-stage renal diseases.J Atheroscler Thromb，2008，15：339-344.
27.	Masugata H，Senda S，Himoto T，et al.Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index.Tohoku J Exp Med，2009，219：101-105.
28.	Sakane K，Miyoshi T，Doi M，et al.Association of new arterial stiffness parameter，the cardio-ankle vascular index，with left ventricular diastolic function.J Atheroscler Thromb，2008，15：261-268.
29.	Shiral K，Utiro J，Otsuka K，et al.A novel blood-pressure-independent arterial wall stiffness parameter：cardio-ankle vascular index.J Atherosoler Thromb，2006，13：101-107.
30.	Yamamoto N，Yamanaka G，Ishikawa M，et al.Cardio-ankle vascular index as a predictor of cogonitive impairment in community-dwelling elderly people：four-year follow-up.Dement Geriatr Cogn Disord，2009，28：153-158.
31.	Kadota K，Takamura N，Aoyagi K，et al.Availability of cardio-ankle vascular index （CAVI） as a screening tool for atherosclerosis.Circ J，2008，72：304-308.
32.	Anderson AD，Uehata A，Gerhard MD，et al.Close relationship of endothelial function in the human coronary and peripheral circulations.Am Coll Cardiol，1995，26：1235-1241.
33.	贾锋鹏，雷寒，覃数.无症状心肌缺血与高敏C反应蛋白和内皮功能失调.中华内科杂志，2007，46：919-922.
34.	林金秀，杨霞，郑小蓉，等.高血压合并代谢综合征患者血管功能及靶器官损害的变化.中华心血管杂志，2007，35：710-714.
35.	Kumagai T，Kasai T，Kato M，et al.Establishment of the cardio-ankle vascular Index in patients with obstructive sleep apnea.Chest，2009，136：779-786.
36.	Bayram NA，Ciftci B，Keles T，et al.Endothelial function in normotensive men with obstructive sleep apnea before and 6 months after CPAP treatment.Sleep，2009，32：1257-1263.
37.	Tanriverdi H，Evrengul H，Kara CO，et al.Aortic stiffness，flow-mediated dilatation and carotid intima-media thickness in obstructive sleep apnea：non-invasive indicators of atherosclerosis.Respiration，2006，73：741-750.
38.	田建立，张蕴，王铮，等.阻塞性睡眠呼吸暂停低通气综合征患者动脉粥样硬化无创检测指标分析.中华结核和呼吸杂志，2006，6：395-398.
39.	Amra B，Karbasi E，Hashemi M，et al.Endothelial dysfunction in patients with obstructive sleep apnoea independent of metabolic syndrome.Ann Acad Med Singapore，2009，38：461-464.

1. Lorenzi-Filho G，Drager LF.Obstructive sleep apnea and atherosclerosis：a new paradigm.Am J Respir Crit Care Med，2007，175：1219-1221.
2. 王菡侨，何权瀛.阻塞性睡眠呼吸暂停综合征与高血压.中国呼吸与危重监护杂志，2008，7：313-317.
3. O’Leary DH，Polak JF，Kronmal RA，et al.Carotidartery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults.N Engl J Med，1999，340：34-42.
4. Takiuchi S，Kamide K，Miwa Y，et al.Diagnostic value of carotid intima-media thickness and plaque score for predicting target organ damage in patients with essential hypertension.J Hum Hypertens，2004，18：17-23.
5. 宝辉，苗懿德，张颖.老年人血尿酸水平与颈动脉粥样硬化程度的相关性研究.中华全科医师杂志，2005，4：13-16.
6. 万里凯，王小燕，张琴，等.年轻人颈动脉内中膜厚度与血压及QT离散度的相关性研究.中华超声影像学杂志，2008，17：858-860.
7. 刘俊，姚欢.高血压病患者颈动脉内膜中层厚度与静息心率的关系.医师进修杂志，2005，28：39-42.
8. 李振光，伍期专，唐朝枢，等.动脉粥样硬化患者颈动脉内膜中层厚度与血浆溶血磷脂酸含量的变化.中华医学杂志，2004，84：1071-1072.
9. 匡鼎伟，丁峰，薛骏，等.维持性血透患者颈动脉内膜中层厚度增厚及其影响因素分析.中华肾脏病杂志，2005，21：577-581.
10. 王云开，魏云峰，王梦洪，等.颈动脉内膜中层增厚患者血清基质金属蛋白酶-9、可溶性P-选择素和高敏C-反应蛋白变化的研究.中国综合临床，2008，24：1241-1243.
11. Kiykim AA，Camsari A，Kahraman S，et al.Increased incidence of carotid artery wall changes and associated variables in hemodialysis patients without symptomatic cardiovascular disease.Yousei Med J，2004，45：247-254.
12. 王新，张磊，饶小胖，等.颈动脉内膜中层厚度影响因素的研究进展.国外医学内分泌学分册，2004，24：423-424.
13. World Health Organization.International society of hypertension guidelines for the management of hypertension.Guidelines Subcommittee.J Hypertens，1999，17：151-183.
14. Hopkins KD，Lehmann ED，Gosling RG.Aortic compliance measurements：a non-invasive indicator of atherosclerosis? Lancet，1994，343：1447.
15. Filipovský J，Tichá M，Cífková R，et al.Large artery stiffness and pulse wave reflection：results of a population-based study.Blood Press，2005，14：45-52.
16. Laurent S，Boutouyrie P，Asmar R，et al.Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients.Hypertension，2001，37：1236-1241.
17. Blacher J，Guerin AP，Pannier B，et al.Impact of aortic stiffness on survival in end stage renal disease.Circulation，1999，99：2434-2439.
18. Cruickshank K，Riste L，Anderson SG，et al.Aortic pulse-wave velocity and its relationship to mortality in diabetes and glucose intolerance：an integrated index of vascular function? Circulation，2002，106：2085-2090.
19. Vaitkevicius PV，Fleg JL，Engel JH，et al.Effects of age and aerobic capacity on arterial stiffness in healthy adults.Circulation，1993，88：1456-1462.
20. Lehmann ED，Watts GF，Gosling RG.Aortic distensibility and hypercholesterolemia.Lancet，1992，340：1171-1172.
21. Lehmann ED，Gosling RG，Sonksen PH.Arterial wall compliance in diabetes.Diabet Med，1992，9：114-119.
22. Rajkumar C，Kingwell BA，Cameron JD，et al.Hormonal therapy increases arterial compliance in postmenopausal women.J Am Coll Cardiol，1997，30：350-356.
23. 孙卫平，吴永全，李觉，等.脉搏波传导速度与冠心病心功能不全的相关性.中华内科杂志，2008，47：382-384.
24. Okura T，Watanabe S，Kurata M，et al.Relationship between cardio-ankle vascular index （CAVI） and carotid atherosclerosis in patients with essential hypertension.Hypertens Res，2007，30：335-340.
25. Satoh N，Shimatsu A，Kato Y，et al.Evaluation of the cardio-ankle Index，a new indicator of arterial stiffness independent of blood pressure，in obesity and metabolic syndrome.Hypertense Res，2008，31：1921-1930.
26. Takenaka T，Hoshi H，Kato N，et al.Cardioankle vascular index to screen cardiovascular diseases in patients with end-stage renal diseases.J Atheroscler Thromb，2008，15：339-344.
27. Masugata H，Senda S，Himoto T，et al.Detection of increased arterial stiffness in a patient with early stage of large vessel vasculitis by measuring cardio-ankle vascular index.Tohoku J Exp Med，2009，219：101-105.
28. Sakane K，Miyoshi T，Doi M，et al.Association of new arterial stiffness parameter，the cardio-ankle vascular index，with left ventricular diastolic function.J Atheroscler Thromb，2008，15：261-268.
29. Shiral K，Utiro J，Otsuka K，et al.A novel blood-pressure-independent arterial wall stiffness parameter：cardio-ankle vascular index.J Atherosoler Thromb，2006，13：101-107.
30. Yamamoto N，Yamanaka G，Ishikawa M，et al.Cardio-ankle vascular index as a predictor of cogonitive impairment in community-dwelling elderly people：four-year follow-up.Dement Geriatr Cogn Disord，2009，28：153-158.
31. Kadota K，Takamura N，Aoyagi K，et al.Availability of cardio-ankle vascular index （CAVI） as a screening tool for atherosclerosis.Circ J，2008，72：304-308.
32. Anderson AD，Uehata A，Gerhard MD，et al.Close relationship of endothelial function in the human coronary and peripheral circulations.Am Coll Cardiol，1995，26：1235-1241.
33. 贾锋鹏，雷寒，覃数.无症状心肌缺血与高敏C反应蛋白和内皮功能失调.中华内科杂志，2007，46：919-922.
34. 林金秀，杨霞，郑小蓉，等.高血压合并代谢综合征患者血管功能及靶器官损害的变化.中华心血管杂志，2007，35：710-714.
35. Kumagai T，Kasai T，Kato M，et al.Establishment of the cardio-ankle vascular Index in patients with obstructive sleep apnea.Chest，2009，136：779-786.
36. Bayram NA，Ciftci B，Keles T，et al.Endothelial function in normotensive men with obstructive sleep apnea before and 6 months after CPAP treatment.Sleep，2009，32：1257-1263.
37. Tanriverdi H，Evrengul H，Kara CO，et al.Aortic stiffness，flow-mediated dilatation and carotid intima-media thickness in obstructive sleep apnea：non-invasive indicators of atherosclerosis.Respiration，2006，73：741-750.
38. 田建立，张蕴，王铮，等.阻塞性睡眠呼吸暂停低通气综合征患者动脉粥样硬化无创检测指标分析.中华结核和呼吸杂志，2006，6：395-398.
39. Amra B，Karbasi E，Hashemi M，et al.Endothelial dysfunction in patients with obstructive sleep apnoea independent of metabolic syndrome.Ann Acad Med Singapore，2009，38：461-464.

Chinese Journal of Respiratory and Critical Care Medicine

Progress of Non-Invasive Arterial Measurements and Evaulation of Cardiovascular Injury of OSAHS

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