肺上皮样血管内皮细胞瘤一例并文献复习_Chinese Journal of Respiratory and Critical Care Medicine

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王玉珠 ¹ , 金洪 ² , 姜勇 ³

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Keywords：

肺上皮样血管内皮细胞瘤; 肺肿

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目的提高对肺上皮样血管内皮细胞瘤临床诊治的认识。方法报告1 例肺上皮样血管内皮细胞瘤病例并进行相关文献复习。结果患者为29 岁男性, 反复咳嗽10 个月。多次胸部CT均显示双肺多发性结节影, 临床诊断为肺癌、结节病、结核。最后经胸腔镜开胸肺活检病理诊断为肺上皮样血管内皮细胞瘤。结合本例并复习近20 年国内外文献报道的110 例肺上皮样血管内皮细胞瘤( 国外96 例, 国内14 例) 资料。结果显示本病女性多见, 发病年龄7 ～83 岁; 咳嗽为常见症状, 胸部CT 表现为结节影。确诊主要依靠手术病理检查。目前尚无有效的治疗措施。结论肺上皮样血管内皮细胞瘤是一种罕见病, 临床无特异性, 极易误诊。

Citation： 王玉珠,金洪,姜勇. 肺上皮样血管内皮细胞瘤一例并文献复习. Chinese Journal of Respiratory and Critical Care Medicine, 2010, 9(6): 641-643. doi: Copy

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3.	叶甫登, 张峰. 肺上皮样血管内皮瘤( 附1 例报告及文献复习) .临床肺科杂志, 2007, 12: 332-334 .
4.	Weiss SW, Ishak KG, Dail DH, et al. Epithelioid hemangioendothelioma and related lesions. Semin Diagn Pathol,1986, 3: 259 -287.
5.	Schattenberg T, Kam R, Klopp M, et al. Pulmonary epithelioid hemangioendothelioma: report of three cases. Surg Today, 2008, 38 :844-849.
6.	Bharadwaj R, Hejmadi R, Desai S. Pericardial effusion and raised CA-125 level-unusual manifestations of primary pulmonary epithelioid hemangioendothelioma. Indian J Cancer, 1999, 36: 194 -197.
7.	Travis WD, Brambilla E, Mueller-Hermelink HK, et al. Pathology and genetics of tumours of the lung, pleure, thymus and heart. WHO classification of tumours. Lyon: IARC Press; 2004 .
8.	Fagen K, Silverman ED, Cole RL. et al. Detection of a pulmonary epithelioid hemangioendothelioma by FDG PET Scan. Clin NuclMed, 2004, 29: 758-759 .
9.	Cronin P, Arenberg D. Pulmonary epithelioid hemangioendothelioma:an unusual case and a review of the literature. Chest, 2004, 125:789-793.
10.	Ross GJ, Violi L, Friedman AC, et al. Intravascular bronchioloalveolar tumor: CT and pathologic correlation. J Comp Assist Tomogr, 1989 ,13: 240-243 .
11.	Hanada N, Namai S, Kobayashi C, et al. Case report of pulmonary epithelioid hemangioendothelioma ( in Japanese ) . Nihon Kokyuki Gakkai Zasshi, 2003, 41: 144-149.
12.	Roudier-Pujol C, Enjolras O, Lacronique J, et al. Multifocal epithelioid hemangioendothelioma with partial remission after interferon alpha-2a treatment( in French) . Ann Dermatol Venerol,1994, 121: 898-904.
13.	Bagan P, Hassan M, Le Pimpec Barthes F, et al. Prognostic factors and surgical indications of pulmonary epithelioid hemangioendothelioma: a review of the literature. Ann Thorac Surg, 2006, 82: 2010-2013.
14.	Kitaichi M, Nagai S, Nishimura K, et al. Pulmonary epithelioid hemangioendothelioma in 21 patients, including three with partial spontaneous regression. Eur Respir J, 1998, 12: 89-96.

1. Dail DH, Liebow AA, Gmelich JT, et al, Intravascular, bronchiolar,and alveolar tumor of the lung( IVBAT) . An analysis of twenty cases of a peculiar sclerosing endothelial tumor. Cancer, 1983, 51 : 452 -464.
2. Amin RM, Hiroshima K, Kokubo T, et al. Risk factors and independent predictors of survival in patients with pulmonary epithelioid hemangioendothelioma. Review of the literature and a case report. Respirology, 2006, 11: 818 -815.
3. 叶甫登, 张峰. 肺上皮样血管内皮瘤( 附1 例报告及文献复习) .临床肺科杂志, 2007, 12: 332-334 .
4. Weiss SW, Ishak KG, Dail DH, et al. Epithelioid hemangioendothelioma and related lesions. Semin Diagn Pathol,1986, 3: 259 -287.
5. Schattenberg T, Kam R, Klopp M, et al. Pulmonary epithelioid hemangioendothelioma: report of three cases. Surg Today, 2008, 38 :844-849.
6. Bharadwaj R, Hejmadi R, Desai S. Pericardial effusion and raised CA-125 level-unusual manifestations of primary pulmonary epithelioid hemangioendothelioma. Indian J Cancer, 1999, 36: 194 -197.
7. Travis WD, Brambilla E, Mueller-Hermelink HK, et al. Pathology and genetics of tumours of the lung, pleure, thymus and heart. WHO classification of tumours. Lyon: IARC Press; 2004 .
8. Fagen K, Silverman ED, Cole RL. et al. Detection of a pulmonary epithelioid hemangioendothelioma by FDG PET Scan. Clin NuclMed, 2004, 29: 758-759 .
9. Cronin P, Arenberg D. Pulmonary epithelioid hemangioendothelioma:an unusual case and a review of the literature. Chest, 2004, 125:789-793.
10. Ross GJ, Violi L, Friedman AC, et al. Intravascular bronchioloalveolar tumor: CT and pathologic correlation. J Comp Assist Tomogr, 1989 ,13: 240-243 .
11. Hanada N, Namai S, Kobayashi C, et al. Case report of pulmonary epithelioid hemangioendothelioma ( in Japanese ) . Nihon Kokyuki Gakkai Zasshi, 2003, 41: 144-149.
12. Roudier-Pujol C, Enjolras O, Lacronique J, et al. Multifocal epithelioid hemangioendothelioma with partial remission after interferon alpha-2a treatment( in French) . Ann Dermatol Venerol,1994, 121: 898-904.
13. Bagan P, Hassan M, Le Pimpec Barthes F, et al. Prognostic factors and surgical indications of pulmonary epithelioid hemangioendothelioma: a review of the literature. Ann Thorac Surg, 2006, 82: 2010-2013.
14. Kitaichi M, Nagai S, Nishimura K, et al. Pulmonary epithelioid hemangioendothelioma in 21 patients, including three with partial spontaneous regression. Eur Respir J, 1998, 12: 89-96.

Chinese Journal of Respiratory and Critical Care Medicine

肺上皮样血管内皮细胞瘤一例并文献复习

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