Objective  To improve the knowledge of epidemiology, diagnosis and treatment of aspirin induced asthma ( AIA) in China.
Methods  Thirty-six cases with AIA who were reported in 30 papers in recent 10 years were analyzed retrospectively.
Results  The drugs which induced AIA in China mainly included acetylsalicylic acid ( aspirin) , ibuprofen ( Fenbid, ibuprofen) , while acetaminophen ( paracetamol,Bufferin, Tylenol ) , phenylpropanoid thiazide ( Piroxicam) , methoxy-naphthalene C acid ( naproxen) ,diclofenac in rare cases. 28. 6% ( 8 /28) of AIA patients were complicated with nasal disease . AIA could occur at all ages, especially for those over 40 years ( 72. 2% , 26 /36) . No significant difference of prevalence
in male and female. The onset time of AIA was less than 60min in 71. 4% and  gt;120min in 38. 6% . Most patients took the medications by oral ( 83. 3% ,30/36) , but the AIA onset time was not different by different administration route.
Conclusions  The incidence of AIA increases in recent years because of widely use of NSAIDs. However, no awareness of NSAIDs induced asthma is common in patients and physicians. For asthma patients it must be caution to take antipyretic analgesic anti-inflammatory drugs. If necessary,methoxy-naphthalene C acid ( naproxen) and diclofenac could be better choice.

Citation： YANG Shusheng,LIN Li.. Aspirin Induced Asthma:A Retrospective Analysis about 36 Cases. Chinese Journal of Respiratory and Critical Care Medicine, 2012, 11(5): 448-451. doi: Copy