LI Zhihua , LIANG Hong , HONG Feng.
  • (Department of Cardiothoracic Surgery, the First Affiliated Hospital， Jinan University,Guangzhou 510630, P.R.China. E-mail: hunterli@163.com);
Ventricular assist device; Collagen; Heart failure; Matrix metalloprotease
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Ventricular assist device can provide the heart with a nonload circumstance and improve hemodynamics and energy metabolism of ischemic myocardium.With ventricular assistance,not only multiple organ failure is improved but also cardiac function and myocardial injury are resumed. In recent years, studies found that ventricular assistance have an impact on the myocardial interstitium on its structural protein-typeⅠ,Ⅲcollagens and their metabolism conditioning systems.It reverse adverse myocardial remodeling and improve cardiac function by changing myocardial collagen content and distribution.

Citation： LI Zhihua,LIANG Hong,HONG Feng.. Progress in Studies of Changes in Myocardial Interstitium after Ventricular Assist Circulation. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2008, 15(4): 293-296. doi: Copy