• (Department of Thoracic and Cardiovascular Surgery, Changhai Hospital, Second Military Medical University, Research Institute of Cardiothoracic Surgery of PLA, Shanghai 200433, P.R. China);
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Objective To summarize the experiences of surgical treatment for periprosthetic leakage(PPL). Methods A total of 63 patients with PPL (mitral PPL in 34, aortic PPL in 29), age 41±12 years, und
erwent reoperation with prosthetic valve replacement from Dec. 1980 to Dec. 2005 in this department. Patient characteristics, operative profiles and follow-up data were described and analyzed in detail. Results The perioperative complications occurred in 11 patients (17.5%), five of whom died (the overall hospital mortality: 7.9%). Fifty-five patients were in close follow-up and three of them lost in that period, five patients died in late. Fifty patients long-term survivals were in New York Heart Association class Ⅰ-Ⅱ and follow-up evaluation by echocardiography showed no evidence of recurrence or residual PPL and PPL-related complications. Conclusion More attention should be paid to the study on etiology, pathophysiology, diagnostic methods, and clinical classification of PPL. For patients with PPL, reoperation with prosthetic valve replacement is considerably effective and can obtain an acceptable longterm results.

Citation: ZHANG Baoren,XU Zhiyun,ZOU Liangjian,HAN Qingqi.. Surgical Treatment of Periprosthetic Leakage: Report of 25year Experience with 63 Cases. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2007, 14(2): 81-84. doi: Copy