BAI Lunhao , WANG Yu , BA Gen.
  • Department of Orthopedics, Shengjing Hospital, China Medical University, Shenyang Liaoning, 110001, P.R.China.;
Cterminal propeptide of collagen type II; Osteoarthritis; Biomarker
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Objective To review the research progress of C terminal propeptide of collagen type II (CTX-II), a osteoarthritis (OA) biomarker. Methods Domestic and international l iterature about CTX-II was reviewed extensively and summarized. Results CTX-II is investigated broadly and has the best performance of all currently available biomarkers. CTX-II is a truly useful biomarker for early diagnosis, prognosis, and measurement of treatment response in OA. Conclusion Single CTX-II may be not sufficient for early diagnosis and prognosis of OA, so a combination of CTX-II and other biomarkers or diagnosis methods is needed.

Citation： BAI Lunhao,WANG Yu,BA Gen.. RESEARCH PROGRESS OF C TERMINAL PROPEPTIDE OF COLLAGEN TYPE II. Chinese Journal of Reparative and Reconstructive Surgery, 2011, 25(1): 66-69. doi: Copy