Objective To review the role of integrin in nervous system injury and its repair, and to analyze the possible mechanisms. Methods Recent l iterature concerning integrin and its role in nervous system injury was reviewed and analyzed. Results Integrin and its related signall ing pathway were involved in nervous system injury, especially hypoxicischemic nervous injury, and their repair processes. Conclusion Intervention of integrin signall ing pathway would be a potential strategy to treat nervous system injury, especially hypoxic-ischemic nervous injury.
Citation: TANG Binzhi,QU Yi,MU Dezhi.. INTEGRIN AND REPAIR FOLLOWING NERVOUS SYSTEM INJURY. Chinese Journal of Reparative and Reconstructive Surgery, 2010, 24(4): 487-491. doi: Copy