• Department of Orthopedic Oncology, Affiliated First Hospital, Sun Yat-sen University, Guangzhou Guangdong, 510080, P.R.China.;
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Objective To evaluate the cl inical outcomes of the wide resection and the functional reconstruction for treating mal ignant tumors of the proximal femur. Methods The cl inical data were analysed from 62 patients with mal ignant tumors of the proximal femur treated between January 1987 and December 2007. There were 29 males and 33 females with a median age of 35 years (range, 14-73 years). In 41 patients with primary mal ignant tumors having a disease course of 0.5-14.0 months, there were 16 cases of osteosarcoma, 7 cases of fibrosaroma, 6 cases of chondrosarcoma, 6 cases of mal ignant fibrous histiocytoma, 4 cases of mesenchymal sarcoma,1 case of Ewing sarcoma, and 1 case of angiosarcoma, including 3 cases of type IB, 2 cases of type IIA, 35 cases of type IIB, and 1 case of type III according to Enneking stage. In 21 patients with metastatic tumors, 16 had a mal ignant tumor history; the disease course was 0.1-28.0 months (3.4 months on average). Radical resection was performed in 9 cases, extensive resection in 39 cases, and marginal resection in 14 cases. After resection, 39 cases underwent reconstruction with prostheses (prostheses group) and 14 cases underwent reconstruction with allograft-prosthetic composites (APC, APC group). Results All incision healed by first intention. Twenty-six cases died of tumor metastasis,their postoperative survive time was 16-56 months (28 months on average). The average follow-up time was 64 months (range, 28-221 months) in 36 survival patients. The local recurrence rate of primary mal ignant tumors was 4.88% (2/41). In prostheses group, dislocation of femoral head occurred in 2 cases, fracture of prosthetic stem in 1 case, hip pain in 3 cases, acetabular wear in 3 cases, and stem loosening in 5 cases. In APC group, nonunion of APC occurred in 3 cases and acetabular wear in 1 case. At last follow-up, the average Musculoskeletal Tumor Society (MSTS) functional scores were 77.69% ± 6.50% in prostheses group
and 85.71% ± 7.45% in APC group, showing significant difference (P  lt; 0.001). Conclusion When the wide resection is
performed for mal ignant tumors of the proximal femur, better local control could be achieved. Compared with econstruction of the prosthesis, the APC reconstruction can provide better function.

Citation: WANG Jin,YIN Junqiang,ZOU Changye,XIE Xianbiao,HUANG Gang,LI Haomiao,SHEN Jingnan,HAN Shiying.. SURGICAL TREATMENT OF PROXIMAL FEMORAL MALIGNANT TUMORS. Chinese Journal of Reparative and Reconstructive Surgery, 2010, 24(7): 881-884. doi: Copy