LI Jiao , QU Yi , MU Dezhi.
  • Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.;
Telomerase reverse transcriptase; Neurological diseases; Neural repair; Telomerase
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Objective To review the research process of telomerase reverse transcriptase (TERT) in the restoration of neurological diseases. Methods The related l iterature on TERT in the restoration of neurological diseases was extensively reviewed and comprehensively analyzed. Results TERT was the significant component of telomerase and the critical regulator of telomerase activity. It played an important role in the pathomechanism of neurological diseases including tumors,
neurodevelopmental deficits, and nerve injury. TERT was becoming a research focus in the reparative therapy of neurological diseases. Conclusion TERT has manifested its great academic significance and appl ication prospects in the reparative therapy of neurological diseases, which deserves a further investigation.

Citation： LI Jiao,QU Yi,MU Dezhi.. RESEARCH PROGRESS OF TELOMERASE REVERSE TRANSCRIPTASE IN RESTORATION OF NEUROLOGICAL DISEASES. Chinese Journal of Reparative and Reconstructive Surgery, 2010, 24(9): 1138-1142. doi: Copy