LIN Zihong 1 , LIN Senhao 2 , HUANG Yingxiong 2 , ZHANG Junlong 2 , FU Ming 1
  • 1Department of Joint Surgery, the First Affiliated Hospital of Zhongshan University, Guangzhou Guangdong, 510080, P.R.China;;
  • 2Zhongshan School of Medicine, Sun Yat-sen University.;
MicroRNAs; Osteoblast; Osteogenesis
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Objective To review the progress, controversy and trend in the regulation and mechanism of the microRNAs (miRNAs) during the osteogenesis. Methods Recent l iterature concerning regulation and mechanism of the miRNAs during the osteogenesis was extensively reviewed, summarized and analyzed. Results Recently miRNAs was a hot topic for osteogenesis. More and more materials showed its important role in ossification, but its definite mechanism was not
clear. Conclusion Osteogenesis can be strengthened by miRNAs technology, which has a bright future and may also provide the molecular mechanism. The study on miRNAs of osteogenesis can provide a model to analyze and compare the osteogenetic effects of novel drugs.

Citation： LIN Zihong,LIN Senhao,HUANG Yingxiong,ZHANG Junlong,FU Ming. DEVELOPMENT OF THE ROLE OF MICRORNAS REGULATION IN OSTEOGENESIS. Chinese Journal of Reparative and Reconstructive Surgery, 2009, 23(1): 111-113. doi: Copy