TANG Binzhi , QU Yi , MU Dezhi.
  • Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu Sichuan, 610041, P.R.China.;
Hypoxia inducible factor 1α; Hypoxic-ischemic; injury Re
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To review the role of hypoxia inducible factor 1α (HIF-1α) in hypoxic-ischemic injury and its repair, and to analyze the possible mechanisms. Methods Recent l iterature on HIF-1α and its role in hypoxic-ischemic injury was reviewed and analyzed. Results HIF-1α was involved in the hypoxic-ischemic injury of various organs or tissues and their repair processes. Conclusion HIF-1α has a potential to treat common cl inical hypoxic-ischemic injuries and has a promising
future for appl ication.

Citation： TANG Binzhi,QU Yi,MU Dezhi.. RESEARCH PROGRESS OF HYPOXIA INDUCIBLE FACTOR 1α IN HYPOXIC-ISCHEMIC INJURY. Chinese Journal of Reparative and Reconstructive Surgery, 2009, 23(6): 755-758. doi: Copy