ZHU Jiang , WANG Yan , DIAO Yongshu.
  • Cancer Center of We st China Hospital，Center of Reproductive Medicine, West China Second UniversityHospital, Sichuan University, Chengdu Sichuan, 610041，P.R.China.;
Embryonic stem cells; Self-renewal; Signaling pathway; Culture system
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Objective To review the latest development of the research on the selfrenwal signaling pathway and culture system in vitro of the embryonic stem cells(ESCs). Methods The recent articlesabout the selfrenewal signaling pathway and culture system in vitro of the ESCs were extensively reviewed. Results Understanding of the molecular mechanism of the selfrenewalin vitro and pluripotency of the ESCs was considered important for developing improved methods of deriving, culturing and differentiating these cells into the cells that could be successfully used in the clinical practice. Conclusion A further research is needed to elucidate the selfrenewal signaling pathway and the pluripotency of the ESCs and the culture systemin vitro forthe human ESCs remains to be further improved and developed.

Citation： ZHU Jiang,WANG Yan,DIAO Yongshu.. SELFRENEWAL SIGNALING PATHWAY AND CULTURE SYSTEM IN VITRO OF EMBRYONIC STEM CELLS. Chinese Journal of Reparative and Reconstructive Surgery, 2007, 21(2): 188-193. doi: Copy