Objective To investigate the effect of limb salvage on treating osteosarcoma with pathological fracture. Methods From October 2002 to January 2003, 2 cases of osteosarcoma with pathological fracture were treated by limb salvage. Intraarterial chemotherapy was given by subcutaneous implantable delivery system with caffeine. Replacement with prosthesis was performed after 5 times of chemotherapy. Results Two patients were followed up for twenty-four months and 21 months respectively. No infection, aseptic loosening, local recurrence or metastasis occurred, and function recovery of joints was satisfactory. Conclusion Limb salvage can be considered in condition that primary osteosarcoma with pathological fracture can be treated by effective and comprehensive chemotherapy.

Citation： LI Dingfeng,CUI Qiu,WANG Lei,et al.. THE EFFECT OF LIMB SALVAGE ON TREATING OSTEOSARCOMA WITH PATHOLOGICAL FRACTURE IN TWO CASES. Chinese Journal of Reparative and Reconstructive Surgery, 2006, 20(1): 30-32. doi: Copy