Objective To review the research progress of osteoblastextracellular matrix(ECM) and its application in bone tissue engineering. Methods The recentrelated literatures were extensively reviewed. Results The ECM was complex in its components. The configuration of cell and cell’s adhesion, migration, proliferation, and differentiation were subject to the ECM. The bioactivity of the tissue engineering products was revealed by ECM, which predicted the product’s efficiency in clinic application. Conclusion ECM has the potential to become the effective index in evaluating tissue engineered products.
Citation： QI Jie,YANG Zhiming.. THE EXTRACELLULAR MATRIX IN BONE TISSUE ENGINEERING. Chinese Journal of Reparative and Reconstructive Surgery, 2006, 20(1): 61-64. doi: Copy