• Shanghai QishengInstitute of Biomaterial &;
  • Technology, Shanghai, 201106, P.R.China;
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Objective To review and evaluate the extensive and further research and the application of the collagenbased biomaterials in the field of clinical medicine. Methods The clinical research and application of collagen-based biomaterials were comprehensively reviewed and evaluated on the basis of the up-to-date publications and our practical experiences in their studies and manufacturing. Results The following five aspects concerned with the collagen-based biomaterials were evaluated: biological property, quality control, formulation of substrate and clinical application, immunogenicity and clinical side effect, and potential of the market development. Conclusion Collgen-based biomaterials have a great potential and market space in their clinical application.

Citation: GU Qisheng.. CLINICAL APPLICATION OF COLLAGEN. Chinese Journal of Reparative and Reconstructive Surgery, 2006, 20(10): 1052-1058. doi: Copy