LIU Yong 1 , CEN Ying 1 , TANG Ying 2 , et al. 1
  • Department　of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041，P. R. China.;
Hypertrophic scar; Keloid; Myofibroblast
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Objective To study the effect of myofibroblast on the development of pathological scar. Methods From 1998 to 2000， 14 cases of keloid(k), 13 cases of hypertrophic scar(HS), and 7 cases of scar were studied through immunohistochemistry and electronical microscope. Results Myofibroblasts were often observed in the hypertrophic HS by electronical microscope, but no myofibroblast was observed in the K and NS. αSMactin was expressed in fibroblast of HS, but was not expressed in K and NS. Conclusion Myofibroblast may play a role in the development of hypertrophic scar. The difference between the absence of myofibroblast in keloid and the invasion of keloid deserves further study.

Citation： LIU Yong,CEN Ying,TANG Ying,et al.. THE ROLE OF MYOFIBROBLAST IN THE DEVELOPMENT OF PATHOLOGICAL SCAR. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(1): 39-41. doi: Copy