• Department of Orthopeadic Surgery, Changzheng Hospital, Second Military Medical nivercity,Shanghai,200003,P.R.China.;
Composite; Carbon fiber; Biological safety
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Objective To evaluate the biological safety of continuous carbonfiber reinforced polyolefin as hard tissue repair material. Methods Biocompatibility of the material was evaluated through hemolysis test, pyrogen test,skin irritation test, cytotoxicity test, ames test,in vitro chromosome aberration test, and bone marrow cells Micronuclei test. Results No obvious hemolysis, pyrogenic characteristics, sensitivity, cytotoxxicity, and mutagenicity were observed. Conclusion The continuous carbonfiber reinforced polyolefin composite material is of good biological safety. It meets all the demand made by biological safety as hardtissue repair material.

Citation： HOU Chunlin,XUE Feng,CHEN Qingquan,et al.. EVALUATION OF BIOLOGICAL SAFEFY OF CONTINUOUS CARBONFIBER REINFORCED POLYOLEFIN AS HARD TISSUE REPAIR. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(1): 45-47. doi: Copy