HAO Peng , XIANG Zhou , YANG Zhiming
  • Department of Orthopedic Surgery, West ChinaHodpital, Sichuan University, Chengdu Sichuan, 610041, P. R. China ;
Tissue engineering; Basic fibroblast growth factor; Tendon
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Objective To review the recent researches of basic fibroblast growth factor (bFGF) in tendon tissue engineering. Methods Recentoriginal related literature was extensively reviewed and analyzed. Results bFGF played an important role in establishing standard tendon tissue engineering cell lines, inducing the compound and analysis of extracellular matrix, enhancing interactions between cells and extracellular matrix and accelerating tissue engineering materials’ neovascularization. Conclusion The progresses in increasing endogenetic bFGF expression, controlling the release of exogenous bFGF and improving the bioutilization of bFGF has laid foundation for wider use of bFGF in tendon tissue engineering.

Citation： HAO Peng,XIANG Zhou,YANG Zhiming. THE APPLICATION OF BASIC FIBROBLAST GROWTH FACTOR IN TENDON TISSUE ENGINEERING. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(11): 915-918. doi: Copy