Objective To review researches on the relation between marrow stromal cells(MSCs) and repair of bone defect. Methods The latest original literatures about marrow stromal cells and their use in the treatment of bone defect were extensively reviewed. Results Marrow stromal cells were induced to osteoblasts under proper conditions and showed the potential of bone formation in vivo. The methods of bone tissue engineering using MSCs as seed cells and gene therapy using MSCs as target cells were bothuseful in the repair of bone defect.Conclusion MSCs have a promising future in the repair of bone defect.
Citation: PENG Songlin,FANG Huang,LUO Yongxiang.. MARROW STROMAL CELLS AND REPAIR OF BONE DEFECT. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(3): 245-248. doi: Copy