YANG Jian , BEI Jian zhong , WANG Shen guo.
  • Center of Molecular Science;;
  • Institute of Chemistry;;
  • Chinese Academy of Science. Beijing;;
  • P. R. China 100080;;
Tissue engineering; Surface modification; Cell affinity; Ammonia plasma treatment
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OBJECTIVE: To modify the surface of poly(D,L-lactide) film by anhydrous ammonia gaseous plasma treatment. METHODS: The changes of contact angles were measured and surface energy were calculated. Mouse 3T3 fibroblast cells were cultured on plasma modified and control poly(D,L-lactide) films. RESULTS: It was found that the hydrophilicity and surface energy of the materials have been increased after plasma treatment. Cell culture results showed that ammonia plasma treatment could promote the cell attachment and cells growth. After 4 days culture, the cells on the plasma treated films were 2-folds quantitatively compared with that of the control films. CONCLUSION: Ammonia plasma treatment can improve the cell affinity to poly(D,L-lactide).

Citation： YANG Jian,BEI Jian zhong,WANG Shen guo.. STUDY ON IMPROVEMENT OF CELL AFFINITY OF POLYMER MATERIALS--MODIFIED POLY(D,L-LACTIDE) BY ANHYDROUS AMMONIA GASEOUS PLASMA. Chinese Journal of Reparative and Reconstructive Surgery, 2001, 15(5): 269-272. doi: Copy