JIN Dan , PEI Guo xian , WANG Qian.
  • Department of Orthopedic and Trauma Surgery;;
  • Nanfang Hospital;;
  • the First Military Medical University. Guangzhou Guangdong;;
  • P.R.China 510515;;
Bone marrow stromal cells; Biomaterials; Biocompatibility; Tissue engineering
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OBJECTIVE To study the biocompatibility on bioactive glass ceramics (BGC) and polylactic acid (PLA) combined with cultured bone marrow stromal cells (BMSCs) in bone tissue engineering. METHODS BMSCs were cultured combined with BGC and PLA in vitro, and the morphological characters, cell proliferation, protein content, and alkaline phosphatase activity were detected. RESULTS: BMSCs could be attached to and extended on both BGC and PLA, and normally grown, proliferated, had active function. BGC could promote cell proliferation. CONCLUSION The results show that both BGC and PLA have good biocompatibility with BMSCs, they can be used as biomaterials for cell transplantation in tissue engineering.

Citation： JIN Dan,PEI Guo xian,WANG Qian.. BIOCOMPATIBILITY STUDIES ON BIOACTIVE GLASS CERAMICS AND POLYLACTIC ACID COMBINED WITH CULTURED BONE MARROW STROMAL CELLS IN VITRO. Chinese Journal of Reparative and Reconstructive Surgery, 2000, 14(1): 39-43. doi: Copy