OBJECTIVE: To review the recent advances of hyaluronic acid and its derivatives in medical application. METHODS: Recent original articles related to hyaluronan derivatives and their medical applications were retrieved extensively. RESULTS: Hyaluronic acid and its derivatives play important roles in visosurgery, arthritis therapy, prevention of adhesion, drug delivery, soft-tissue dilation, and percutaneous embolization. CONCLUSION: Development of hyaluronan derivatives may widen their medical application.
Citation： JIANG Lixia,WANG Wenbin.. MEDICAL APPLICATION OF HYALURONIC ACID AND ITS DERIVATIVES. Chinese Journal of Reparative and Reconstructive Surgery, 2000, 14(5): 315-317. doi: Copy