Objective To observe the clinical characteristics and treatment outcomes of aggressive posterior retinopathy of prematurity(AP-ROP). Methods Thirty-five eyes (18 patients) diagnosed with AP-ROP were studied from January 2006 to January 2011. All the patients were examined by 28 D optical lens, sclera compressor and wide-angle digital retinal imaging system (RetCamⅡ). Laser photocoagulation with 532 nm wavelength using binocular indirect ophthalmoscope was used in all the infants within 12 hours after confirmed diagnosis. Thirteen eyes (37.1%) progressed to retinal detachment after laser photocoagulations were surgically treated, while 22 eyes (62.9%) underwent laser photocoagulation alone. Followup ranged from 6 months to 5 years, with a mean of 23.5 months. Results All AP-ROP lesions are located in zone 1 and posterior zone 2, with substantial dilated and tortuous retinal vessels. It is difficult to distinguish between the retinal vein and small arteries. There are shunts from vessel to vessel within the retina and no clear boundary between the vascularized and non-vascularized retina. Neovascularization lesions are flat and hard to be identified. There are no demarcation ridges. After laser treatment, 22 eyes achieved good outcomes. Among 13 eyes who received vitrectomy, 8 eyes achieved retinal reattachment after surgery, while 5 eyes developed total retinal detachment. Conclusion AP-ROP has specific clinical manifestations. Timely laser photocoagulation and early surgical treatment is necessary for AP-ROP.
Citation： 黄欣,单海冬,常青,赵培泉. Clinical characteristics and treatment outcomes of aggressive posterior retinopathy of prematurity. Chinese Journal of Ocular Fundus Diseases, 2012, 28(1): 33-36. doi: Copy