Objective To observe the features of frequency domain optical coherence tomography (FD-OCT) in acute central serous chorioretinopathy (CSC). Methods The data of FD-OCT and fundus fluorescein angiography (FFA) of 31 patients with unilateral acute CSC were retrospectively analyzed. The FD-OCT of retinal pigment epithelial (RPE) layer at leakage points, retinal detachment area and RPE layer in the fellow eyes was documented. Results Thirty-four leakage points were detected in 31 eyes on FFA. At the sites of fluorescein leakage, FD-OCT showed that serous pigment epithelial detachment (PED) in 18 leakage points (52.9%) and 17 eyes (54.8%), a small RPE protrusion in 8 leakage points (23.5%) and 8 eyes (25.8%), RPE irregularity in 6 leakage points (17.6%) and 4 eyes (12.9%) and no detectable RPE abnormality in 2 leakage points (5.9%) and 2 eyes (6.5%). An RPE defect at the edge of or within the PED was found in 7 leakage points (20.6%) and 7 eyes (22.6%). Serous retinal detachment and interruption or complete disappearance of the hyperreflective inner/outer segment junction (IS/OS) were detected in all diseased eyes. Uneven thickness of the outer segments (OS) was found in 24 eyes (77.4%), 14 of which had sagging sign. Flaking of the OS was found in 10 eyes (32.3%), multiple hyperreflective dots on the posterior surface of the detached neurosensory retina and on the surface of the RPE were found in 8 eyes (25.8%). Among 31 fellow eyes, FD-OCT also showed RPE abnormalities in 11 eyes (35.5%), in which PED, RPE protrusion and RPE irregularity were detected in 2 (6.5%), 1 (3.2%) and 8 eyes (25.8%), respectively. Conclusions In acute CSC the FD-OCT images at leakage points of are featured by PED, RPE protrusion, RPE irregularity and no detectable RPE abnormality; in retinal detachment area FD-OCT are featured by serous retinal detachment, interruption or disappearance of IS/OS, uneven thickness of OS, flaking of OS and hyper-reflective dots on the posterior surface of the detached neurosensory retina and on the surface of the RPE.
Citation： 赵潺,董方田,高洁,郑霖,于伟泓,戴荣平,张枝桥. Features of frequency domain optical coherence tomography in acute central serous chorioretinopathy. Chinese Journal of Ocular Fundus Diseases, 2011, 27(4): 318-322. doi: Copy