Objective To observe the types and features of Bruch prime;s membrane (BM) in the choriocapillarioBruch prime;s membraneretinal pigment epithelium complex (CBRP-C) in central serous chorioretinopathy (CSC) by optical coherence tomography (OCT). Methods This is a retrospective case control study. Sixty eyes of 60 patients (43 males, 17 females) with CSC who underwent laser photocoagulation (51 eyes) or half-dose verteporfin photodynamic therapy (9 eyes) were enrolled. The macular area of all the patients was scanned by SpectralisOCT before and after the treatment, BM was observed as the core indicators of CBRP-C. According to the reflection band,BM was classified into distinguishable BM and indistinguishable BM. The distinguishable BM was classified into phenotype BM (with a subRPE fluid cavity) and cryptotype BM (without a sub-RPE fluid cavity). The types and features of BM in CBRPC of CSC patients before and after the treatment were comparatively analyzed. Results Before the treatment, distinguishable BM were observed in all patients, including 59 eyes (98.3％) with phenotype BM and 1 eye (1.7％) with cryptotype BM. At 1 month after laser photocoagulation, there were, 1/51 eye (2.0%) with indistinguishable BM, and 50/51 eyes (98.0%) with distinguishable BM, including 34 eyes (68.0%) with phenotype BM and 16 eyes (32.0%) with cryptotype BM. At 1 month after half-dose PDT, there were 1/9 eye (11.1%) with indistinguishable BM and 8/9 eyes (88.9%) with distinguishable BM, including 1 eye (12.5%) with phenotype BM and 7 eyes (87.5%) with cryptotype BM. Conclusion The phenotype BM exists in CSC patients before and after the treatment, but it has been improved after treatment.
Citation： 周容,贾晓林,孙祖华,林冰,高伟娜,郑微微,李英姿,刘晓玲. Classification of Bruch′s membrane in the choriocapillario-Bruch′s membrane-retinal pigment epithelium complex in central serous chorioretinopathy by optical coherence tomography. Chinese Journal of Ocular Fundus Diseases, 2011, 27(4): 323-326. doi: Copy