Objective To observe the choroidal thickness and its relationship with age and refraction status in Chinese population. Methods 180 healthy volunteers (360 eyes) were enrolled in this study. Based on the age, the volunteers were divided into A (20-29 years old), B (30-39 year old), C (40-49 years old), D (50-59 year old), E (60-69 year old), and F (70-85 year old) group, with 33, 31, 29, 30, 31, 26 volunteers respectively. And the volunteers were divided into ＜60 years old group with 123 volunteers and ge; 60 years old group with 57 volunteers. Enhanced depth imaging (EDI) choroidal scans were obtained in all eyes by using spectraldomain optical coherence tomography. Subfoveal choroidal thickness (CT) and CT at 1 mm/3 mm temporal, nasal, superior, inferior to the fovea (S 1 mm, I1 mm, T1 mm, N 1 mm, S, I3 mm, T3 mm, N3 mm) were measured. The differences of CT between different quadrants, genders, eyes and ages were comparatively analyzed. The correlations between age, refraction status and CT in the volunteers of ＜60 years old and ge; 60 years old group were analyzed. Results The subfoveal CT was (262.78 plusmn;84.38) mu;m. The differences were significant between subfoveal CT and all the quadrants CT (P＜0.05) except for S1 mm and T1 mm (P＞0.05 ). There was no difference between genders or eyes in subfoveal CT (P＞0.05 ). There was no difference between A, B, C, D group in subfoveal CT (P＞0.05 ). The subfoveal CT of E and F group were thinner than A, B, C, D group (P＜0.05). In the ＜60 years old group, there was a positive correlation between refraction status and CT (r=0.147,P＜0.05); but no correlation between age and CT (r=－0.055, P＞0.05 ). In the ge; 60 years old group, there was a significant negative correlation between CT and age (r=－0.543, P＜0.05), but no correlation between refraction status and CT (r=-0.008, P＞0.05). Conclusions The average subfoveal CT in Chinese population was (262.78 plusmn;84.38) mu;m. The refraction status is the main influence factors in subjects ＜60 years old, while the age is the main influence factors in subjects ge;60 years old.
Citation： 曾婧,丁小燕,李加青,刘冉,马伟,潘间英,唐仕波. Choroidal thickness of Chinese population and its relevant factors. Chinese Journal of Ocular Fundus Diseases, 2011, 27(5): 450-453. doi: Copy