• Shenzhen Eye Hospital, Shenzhen Ophthalmic Center, College of Jinan University, Sh enzhen 518001, China;
Retinopathy of prematurity/epidemiology; Retinopathy of prematurity/etiology; Retinopathy of prematurity/diagnosis; Neonatal Scree ning
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Objective To learn the screening results of retinopathy o f prematur ity (ROP) of the preterm infants in three hospitals in Shenzhen. Metho ds From Jan. 2004 to Jan. 2007, 1372 preterm infants (2744 eyes) with birth weight  lt;200 0 g or but the ones having severe systemic disease in Shenzhen People's Hospita l, Shenzhen Maternity and Child Healthcare Hospital and Shenzhen Eye Hospital we re screened for ROP with binocular indirect ophthalmoscope and (or) widefield digital pediatric retinal imaging system (RetCamII). Cryotherapy or laser photoco agulation was performed if threshold or pre-threshold type I ROP was found. All preterm infants were followed up until retina is completely vascularized or the disease regressed. Results In all the infants, 218 cases (436 eyes) (15.9％) developed ROP, including 190 eyes (6.9％) suffering from threshold or pre-threshold type 1 ROP, 16 eyes (0.6％) from stage 4 or stage 5, and 230 eyes (8.4％) from stages below threshold or pre-threshold type 1 ROP. There were 435 infants ( 870 eyes) (31.7%) with BW of 1500g or less, in which 236 eyes (27.1％) developed ROP, including 126 eyes (14.5％) suffering from threshold or pre-threshold type 1 ROP, 10 eyes (1.1％) from stage 4 or stage 5, and 100 eyes (11.5％) from stages below threshold or pre-threshold type 1 ROP. There were 137 infants 274 eyes (10%) with BW of 1250g or less, in which 108 eyes (39.4％) developed ROP, including 60 eyes (21.9％) suffering from th reshold or pre-threshold type 1 ROP, 4 eyes (1.4％) from stage 4 or stage 5, and 44 eyes (16％) from stages below threshold or pre-threshold type 1 ROP. Th eincidence of ROP（ chi;2=60.43，P lt;0.001）, the incidence of threshold or pre-threshold type 1 ROP（ chi;2=46.82，P lt;0.001）and the incidence of below threshold or pre-threshold type 1 ROP （ chi;2=10.71，P=0.005）among the total group, BW le;1500g group and BW le;1250g group had statistical differences. Conclusions The incidence of ROP in the three hospitals in Shenzhen was lower. However, the incidence of severe ROP (threshold or pre-threshold type 1 ROP) was higher. Birth weight is an important factor to affect ROP incidence.

Citation： ZHANG Guoming,ZENG Jian,HUANG Lina,et al.. Screening results of retinopathy of prematurity in preterm infants in 3 hospital s in Shenzhen. Chinese Journal of Ocular Fundus Diseases, 2008, 24(1): 38-40. doi: Copy