YIN Xiaolei , JI Shuxing , CHEN Chunlin , et al
  • Department of Ophthalmology，Daping Hospital，Third Military Medical University;
Retina; Receptors, Lipoprotein; Fluoroimmunoassay/method; Microscopy, confocal
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Objective  To observe the expression of Nogo66 receptor （NgR）in rats prime; retina during the postnatal development． Methods  The expression of NgR in 48 rats were observed by immunofluorescence histochemistry and laserconfocal microscopy 0, 3, 7, 14, 21, 35, 49, 63 days after birth, with 6 rats in each group, respectively． Results  The expression of NgR is positive in the retina in the whole duration of growth, and the fluorescence pigmentation was located around the ganglion cell nuclaear. Conclusion  The positive expression of NgR suggests that the interaction of NgR and CNS myelin inhibitors not only inhibit neuronal plasticity but also promote it, which could regulate neuronal plasticity.

Citation： YIN Xiaolei,JI Shuxing,CHEN Chunlin,et al. Expression of Nogo receptor in rats′ retina during the postnatal development. Chinese Journal of Ocular Fundus Diseases, 2007, 23(6): 426-428. doi: Copy