WANG Qiu , WANG Guiyun , ZHANG Xiaoguang.
  • Department of Ophthalmol ogy, the Second Clinical College, Norman Bethune University of Medical Sciences, Changchun 130041,China;
Vitreoretinopathy,proliferative/physiopatho logy; Fibronectins; Antigens,CD29; Immunohistochemistry
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Objective To study the expression of the fibronectin (FN) and  beta;1 integrin ( beta;1) in epiretinal membranes(ERM) of eyes with proliferative vitreoretinopathy(PVR). Methods wenty epiretinal membranes were obtained from eyes undergone vitrectomy for retinal detachment complicated with PVR and observed by immunohistochemical methods. Results Overexpression of FN and  beta;1 were observed in 18 and 16 membranes respectively． Conclusion The synergism of FN and  beta;1 in their action mignt be one of the important roles in the development of PVR. (Chin J Ocul Fundus Dis, 2001,17:119-121)

Citation： WANG Qiu,WANG Guiyun,ZHANG Xiaoguang.. Studies on the expression of fibronectin and integrins in epiretinal membranes　. Chinese Journal of Ocular Fundus Diseases, 2001, 17(2): 119-121. doi: Copy