Objective To evaluate the treatment of surgery and high-dose corticosteroid relevant factors to prognosis in traumatic optic neuropathy. Methods Forty patients(40 eyes) with traumatic optic neuropathy were enrolled.Optic nerve decompression using　transcranial approaches,sinus endoscopy and orbital-ethmoidal sinus rout were performed in 14 patients.Eleven patients were treated with high-dose corticosteroids (5 cases with 1 mg/kg dexamethasone,6 cases with 30 mg/kg methylprednisolone) and 15 patients received nonspecific management chose by themselves.The outcomes of visual acuity in short term and final stage were compared between surgery,high-dose corticosteroid and nonspecific treatment.Multiple variable analysis was done to determine the factors affecting the outcome of visual acuity. Results No light perception were found in 19 cases (19 out of 44 cases,47.5%),whereas visual acuity was light perception to 0.02 in 12 cases　(30.0%)　and 0.05 or better in 9 cases　(22.5%).The odds ratio of high-dose corticosteroid to nonspecific therapy was 2.96　(P=0.0125).The final visual acuity in patients treated with high-dose corticosteroid were better than other two groups (P=0.005,P=0.023,respectively).The short term　(within 3 days)　effective rate was higher in corticosteroid therapy group than operated group　(P=0.024).No light perception following optic nerve trauma appeared to be more danger as 2.14 folds　(P=0.0349)　than those with light perception or better in term of final visual acuity outcome. Conclusions High-dose corticosteroid may be benefit to traumatic optic neuropathy.The treatment in traumatic optic neuropathy using optic nerve decompression needs to be determined.No light perception at initial is an important risk factor in the outcome. (Chin J Ocul Fundus Dis,2000,16:75-77)

Citation： MA Zhizhong,LIU Tiecheng,WEI Shaopo,et al.. Assessment of surgical and high-dose corticosteroid treatment in traumatic optic neuropathy. Chinese Journal of Ocular Fundus Diseases, 2000, 16(2): 75-77. doi: Copy