• Zhongshan Ophthalmic Center,Sun Yat-sen University of Medical Sciences,Guangzhou 510060;
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Flicker and photopic eletroretinogram(ERG)were recorded for 45 eyes of dry type of age-related macular degeneration(AMD)and 24 eyes of wet type of AMD respectively,the amplitud and phase of fundamental response compomeng(30Hz)by discrete Fourier tranform(DFT)were analysed.The abnormality ratios of phases and amplitudes in fundamental responses,amplitudes of photopic white or red b-waves were 48.89%,8.89%,10.11% and 8.89% respectively.The visual acuities of 24 eyes were 1.0 or better,the abnormality ratios of phases were up to 37.50%.These suggest that the change of phases is a sensitive method for detecting the early abnormality of visual function in AMD.The abnormality ratios of phases and amplitudes in fundamental responses were 62.5% and 45.84% in wet type of AMD.The differences between dry type and wet type in amplitudes of fundamental responses and photopic b-waves were statistically significant(P<0.01).This shows that the change of amplitudes is associated with the degree of pathological change of AMD. (Chin J Ocul Fundus Dis,1996,12: 41-43)

Citation: Wen Feng,Wu Dezheng,Wu Lezheng,et al.. THE FLICKER AND PHOTPIC ELECTRORETINOGRAM IN AGE-RELATED MACULAR DEGENERATION. Chinese Journal of Ocular Fundus Diseases, 1996, 12(1): 41-43. doi: Copy