We compared the sensitivities of human embryo conjtmctival fihroblasts(HECF)and rabbit conjunctival fibroblasts(RCF)m five anlineoplasties in vitro.When the concentration of vincrismum and doxorubicin was 0.001~10mg/L.5-FU was 1~1000mg/L and cisplatin was 0.01~10mg/L,the sensitivities of HECF to tile drugs were lower than that of RCF (P lt;0.01).while the difference of the sensitivilics be;ween HECF and RCF to VP-16 was not significant (P<0.05). The results suggested that the selection of therapeutic agents for intraocular proliferative disease wilh'hunmn conjunctiva fihroblasts may be more valuable than that with RCF. (Chin J Ocul Fundus Dis,1994,10:223-225)
Citation: Li Qiuming,Sun Xiuwen,Chen Meilan,et al.. DIFFERENCE IN SENSITIVITIES OF CONJUNCTIVA FIBROBLASTS OF HUMAN EMBRYO AND RABBIT TO ANTINEOPLASTICS. Chinese Journal of Ocular Fundus Diseases, 1994, 10(4): 223-225. doi: Copy