- 1. West China Hospital of Sichuan University,Chengdu, 610041,China2.Chengdu University of Traditional Chinese Medicine, Chengdu, 610041,China;
Objective To assess the quality of published systematic reviews and meta-analyses on Traditional Chinese Medicine (TCM) published in Chinese journals.
Methods We searched CNKI, CMB from January 1995 to December 2006 and The Cochrane Library (Issue 4, 2006) for systematic reviews and meta-analyses on TCM. We extracted details of the interventions used in the treatment and control groups, analyzed the validity of included studies and investigated whether the reports used QUOROM statement or not.
Results We identified 111 reports, of which 1 on prevention, 1 on adverse events, 1 on risk factors and premonitory symptoms, 2 on physiochemical parameters, and 106 on effectiveness and safety assessment. In total, 42 types of diseases were involved, and 41 reports were related to cerebrovascular diseases. As for the investigated interventions, 25 studies assessed TCM and 12 assessed acupuncture. Two had no control intervention design control in the group, 15 did not describe the interventions in the control group, 50 used active control (26 for western medicine, 12 for Chinese medicine, 12 for western plus Chinese medicine), 14 used blank control, 17 used baseline control, 4 used sham acupuncture or acupoint injection control etc., 5 used placebo control and 4 used "mutual control". The interventions used in the treatment and control groups varied widely. The number of trials included in the reviews and meta-analyses ranged from 1 to 35, and 24 studies included non-randomized controlled trials. Of the 111 reports, 14 were Cochrane reviews, 16 did not assess the quality of included randomized trials and a further 22 performed only simple and nonstandard quality assessment of the included trials. None of the reviews or meta-analyses used the QUOROM statement to report their results. Conclusions Because of the unique characteristics of TCM, systematic reviews of TCM should focus on a specific topic, avoid the selection of too many drugs, address the target indications of the test drugs and pay attention on intervention evaluation. High quality systematic reviews of TCM are needed but they will only be produced through the concerted efforts of clinicians, TCM practitioners and methodologists.
Citation: LI Tingqian,LIU Xuemei,ZHANG Mingming,MA Jianxin,DU Liang,ZHOU Youdan,CHANG Jing,WANG Lei,YANG Xiaonan,WANG Gang,ZHANG Ying. Assessment of Systematic Reviews and Meta-analyses on Traditional Chinese Medicine Published in Chinese Journals. Chinese Journal of Evidence-Based Medicine, 2007, 07(3): 180-188. doi: Copy
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136. | 王汉蓉, 岑小波, 王莉. 安宫牛黄丸治疗肺性脑病的系统评价. 中草药, 2003, 34(1): 92~73. |
137. | 李国春. 半夏泻心汤治疗慢性胃炎随机对照试验的Meta分析. 循证医学, 2004, 4(1): 14~21. |
138. | 许卫华, 王宝娟, 何羿婷, 等. 以非甾体抗炎药为对照的中药治疗类风湿性关节炎文献系统评价. 中国中医基础医学杂志, 2004, 10(1): 20~25. |
139. | 陈砺, 朱春燕, 王小平, 等. 补肾中药对绝经后骨质疏松症患者骨密度影响的Meta分析. 中国临床康复, 2004, 8(30): 6703~6705. |
140. | 冉兴无, 李宁, 刘雅. 川芎嗪治疗糖尿病周围神经病变的系统评价. 中国循证医学杂志, 2004, 4(6): 393~397. |
141. | 陈瑶, 刘鸣. 川芎嗪治疗脑梗死: 疗效及安全性的系统评价. 中国临床康复, 2004, 8(7): 1299~1301. |
142. | 赵娜, 董碧蓉, 须晋, 等. 中西医结合治疗严重急性呼吸综合征(SARS) 疗效的系统评价. 华西医学, 2004, 19(3): 353~357. |
143. | 简讯, 樊均明, 李孜, 等. 川芎嗪治疗原发性肾病综合征的系统评价. 中国循证医学杂志, 2004, 4(8): 627~633. |
144. | 钱晓路, 袁浩斌, 张美娟. 中医药治疗压疮随机对照试验的Meta分析. 护理研究2004, 18(4): 568~570. |
145. | 李慧, 梁伟雄, 郭新峰. 醒脑开窍针法治疗中风的Meta分析. 广州中医药大学学报, 2004, 21(3): 215~219. |
146. | 沈朝斌, 顾珺, 林千里, 等. 中医药对创伤修复作用的Meta分析. 上海中医药杂志, 2004, 38(3): 56~59. |
147. | 孙雪峰, 苏金环, 叶任高. 中西医结合治疗狼疮性肾炎的荟萃分析. 中国现代医学杂志, 2004, 14(17): 23~28. |
148. | 陈力, 杜宝新, 黄燕, 等. 复方丹参注射治疗脑中风的Meta-分析. 江西中医学院学报, 2004, 16(5): 75~78. |
149. | 贺豪杰, 李尚为, 许良智, 等. 中草药治疗输卵管阻塞性不孕的系统评价. 中国循证医学杂志, 2004, 4(4): 244~248. |
150. | 彭唯娜, 赵宏, 刘志顺, 等. 电针治疗血管性痴呆的系统评价. 中国针灸, 2004, 24(5): 297~301. |
151. | 王蕾, 熊泽宇, 王刚, 等. 复方丹参滴丸治疗稳定型心绞痛随机对照试验的系统评价. 中国中西医结合杂志, 2004, 24(6): 500~504. |
152. | 李孜, 卿平, 冀玲, 等. 大黄治疗慢性肾功能衰竭的系统评价. 中国循证医学杂志 2004, 4(7): 468~473. |
153. | 张敏州, 王磊, 陈伯钧, 等. 复方丹参滴丸治疗稳定型心绞痛Meta分析. 中西医结合心脑血管病杂志, 2004, 2(6): 311~314. |
154. | 王雪, 李素霞, 祝三平, 等. 福康片治疗阿片类戒断症状的疗效及安全性评价. 中国循证医学杂志, 2004, 4(8): 545~549. |
155. | 王红静, 黄倩, 安寒, 等. 中草药治疗子宫内膜异位症的系统评价. 中国循证医学杂志, 2004, 4(9): 602~608. |
156. | 贺豪杰, 许良智, 李尚为, 等. 中草药治疗女性免疫性不孕的系统评价. 中国循证医学杂志, 2004, 4(9): 609~614. |
157. | 王林, 周仕轶, 邵继春, 等. 补肾活血类中药复方治疗良性前列腺增生的系统评价. 中华男科学杂志, 2004, 10(10): 785~789. |
158. | 聂广宁, 王小云, 杨洪艳, 等. 中医药治疗更年期综合征的系统评价. 中医药通报, 2004, 3(5): 10~16. |
159. | 周贤刚, 王宏伟, 余广彬, 等. 麝香保心丸治疗冠心病心绞痛的Meta-分析. 中成药, 2004, (26): 1~6. |
160. | 马凌, 翁燕娜, 肖昕. 中医药联合化疗治疗进展期非小细胞肺癌近期疗效和生存质量的META分析. 中华实用中西医杂志, 2004, 4(17): 709~712. |
161. | 陈卫平, 吕红, 舒志军. 玉屏风散与T细胞亚型表达的Meta分析. 上海中医药杂志, 2004, 38(11): 59~61. |
162. | 田浩明, 魏东, 贾海燕. 葛根素治疗糖尿病周围神经病变的系统评价. 中国循证医学杂志, 2004, 4(8): 556~569. |
163. | 吴泰相, 刘保延, 刘关键, 等. 中西医结合治疗SARS疗效的系统评价. 中国循证医学杂志, 2004, 4(4): 226~238. |
164. | 刘晓雁, 赖世隆, 郭新峰, 等. 参麦注射液辅助肿瘤化疗的系统评价. 中国循证医学杂志, 2005, 5(1): 22~28. |
165. | 李宁, 吴滨, 王成伟, 等. 针灸治疗失眠症随机对照试验的系统评价. 中国针灸, 2005, 25(1): 7~10. |
166. | 谢雁鸣, 朱芸茵, 吴泰相. 中医药治疗绝经后骨质疏松的疗效及安全性系统评价. 中国循证医学杂志, 2005, 5(1): 29~34. |
167. | 吴波, 刘鸣, 张世洪. 丹参类药物治疗急性缺血性脑卒中的系统评价. 中国循证医学杂志, 2005, 5(2): 101~105. |
168. | 陈弼沧, 吴秋英, 王丽英, 等. 葛根素注射液治疗糖尿病周围神经病变的Meta分析. 福建中医药, 2005, 36(1): 32~34. |
169. | 李漾, 罗纯. 针刺治疗紧张性头痛疗效的系统评价. 中国循证医学杂志, 2005, 5(2): 117~124. |
170. | 何俐, 周沐科, 周东, 等. 针灸治疗Bell’s面瘫疗效的系统评价. 中国循证医学杂志, 2005, 5(2): 106~109. |
171. | 刘宇, 吴胜丹, 李瑛. 中药治疗绝经后骨质疏松症的系统评价. 海南医学, 2005, 16(2): 136~137. |
172. | 刘云霞, 王浩英, 庞春坤, 等. 中草药治疗脂肪肝随机对照试验的系统评价. 循证医学, 2005, 5(1): 29~32. |
173. | 曹文斋, 兰德, 张婷, 等. 灯盏花注射液治疗心绞痛疗效的系统评价. 中国循证医学杂志, 2005, 5(4): 317~322. |
174. | 郝艳会, 洪军, 寇长贵, 等. 中西医结合与单纯西医治疗SARS的Meta分析. 中国公共卫生, 2005, 21(5): 525~526. |
175. | 黄宇虹, 胡镜清, 高秀梅, 等. 复方丹参注射液配伍黄芪注射液治疗冠心病疗效Meta分析. 天津中医药, 2005, 22(5): 375~377. |
176. | 陈军, 陈辉扬, 刘志承, 等. 茵栀黄注射对黄疸型病毒性肝炎的退黄效果与安全性的系统评价. 中国循证医学杂志, 2005, 5(6): 461~465. |
177. | 刘向前, 姚共和, 杨少锋, 等. 以NSAIDs为对照中药治疗膝关节骨关节炎文献的系统评价. 中医药学刊, 2005, 23(6): 1008~1012. |
178. | 罗胜, 罗思文. 针灸治疗腰椎间盘突出症的系统分析. 针灸临床杂志, 2005, 21(6): 10~14. |
179. | 许风雷, 高丽霞, 吴泰相, 等. 醒脑静注射液治疗脑梗塞临床疗效及安全性随机对照试验的系统评价. 中国循证医学杂志, 2005, 5(7): 549~565. |
180. | 岳冀蓉, 吴泰相, 董碧蓉. 智灵汤治疗血管性痴呆的系统评价. 中国循证医学杂志, 2005, 5(9): 692~695. |
181. | 李博, 李峰, 吴泰相. 参附脱毒胶囊治疗阿片类急性戒断综合征的系统评价. 中国循证医学杂志, 2005, 5(9): 684~691. |
182. | 于金娜, 刘保延, 刘志顺, 等. 针刺治疗经前期综合征的临床疗效和安全性评价. 中国针灸, 2005, 25(6): 377~382. |
183. | 朱泉, 江魏. 中医补肾法提高男性血清睾酮水平的研究. 医学信息, 2005, 18(9): 1153~1155. |
184. | 张世洪, 刘鸣, 李林. 针刺治疗急性脑卒中随机或半随机对照试验的Cochrane系统评价. 中国临床康复, 2005, 9(9): 108~110. |
185. | 刘建平, Eric Manheimer, 施毅, 等. 中西医结合治疗SARS的系统评价与Meta-分析. 中国中西医结合杂志, 2005, 25(12): 1082~1088. |
186. | 刘增巍, 张星星. 中药治疗胃癌前病变疗效的荟萃分析. 现代中西医结合杂志, 2005, 14(21): 2818~2820. |
187. | 张伟, 张心月, 王新东, 等. 鱼腥草注射液治疗呼吸系统感染的Meta分析. 中国药学杂志, 2005, 40(21): 1674~1677. |
188. | 周贤刚, 杨闯, 杨丽霞, 等. 中药穴位贴敷治疗面瘫的Meta-分析. 中国针灸, 2005, 25(11): 797~802. |
189. | 李永健, 陈红风, 邸若虹, 等. 中医药治疗乳腺增生病随机对照临床试验系统评价. 中国中医药信息杂志, 2005, 12(12): 98~99. |
190. | 李勉珊, 王杰松, 李保卫, 等. 葛根素注射液治疗突发性耳聋的Meta分析. 中国药房, 2006, 17(1): 44~46. |
191. | 方润权, 黄雪梅. 杏丁注射液改善急性脑梗死患者运动功能的系统评价. 中国现代医药杂志, 2006, 8(3): 32~34. |
192. | 王丽平, 解越. 针灸治疗卒中后吞咽困难的系统评价. 中国针灸, 2006, 26(2): 141~146. |
193. | 王昕, 朱云茵, 胡立胜. 中医药治疗血管性痴呆的系统评价. 南京中医药大学学报, 2006, 22(3): 181~182. |
194. | 王杰松, 张俊虎, 胡慧渊, 等. 三七总皂苷和复方丹参注射液治疗脑梗死的Meta分析. 中国医院药学杂志, 2006, 26(3): 317-319. |
195. | 刘为民, 刘保延, 谢雁鸣, 等. 疏血通注射液治疗脑梗塞的系统评价. 中国循证医学杂志, 2006, 6(4): 261~266. |
196. | 王卫霞, 陈可冀. 血脂康胶囊治疗高脂血症有效性和安全性的系统评价. 中国循证医学杂志, 2006, 6(5): 352-360. |
197. | 杨光, 王新卷. 电针治疗颈椎病疗效的系统评价. 北京中医, 2005, 25(7): 433~435. |
198. | 谭燕, 刘鸣, 吴波. 葛根素治疗急性脑梗死的系统评价. 中国循证医学杂志, 2006, 6(7): 494~499. |
199. | 郑明, 苏培华. 支气管哮喘中医药治疗性研究文献的系统评价. 医药产业资讯, 2006, 3(9): 22~24. |
200. | 姜挺, 夏冰, 李春, 等. 中药保留灌肠治疗溃疡性结肠炎疗效的系统评价. 医药导报, 2006, 25(10): 1016~1019. |
201. | 许风雷, 环文英, 吴泰相, 等. 冬虫夏草治疗慢性肾病临床疗效的系统评价. 中国循证医学杂志, 2006, 6(11): 804~808. |
202. | 李可建. 灯盏花制剂治疗缺血性中风急性期随机对照试验的系统评价. 中国医药导刊, 2006, 8(1): 41~44. |
203. | 李可建. 葛根素治疗缺血性中风急性期随机对照试验的系统评价. 山东中医药大学学报, 2006, 30(2): 120~124. |
204. | 李可建. 补阳还五汤及其中成药治疗缺血性中风急性期随机对照试验的系统评价. 中成药, 2006, 28(1): 58~63. |
205. | 李可建. 醒脑静注射液治疗缺血性中风急性期随机对照试验的系统评价. 泰山医学院学报, 2006, 27(4): 310~312. |
206. | 李可建. 参麦注射液治疗缺血性中风急性期随机对照试验的系统评价. 中医药学报, 2006, 34(4): 4~7. |
207. | 李可建. 安宫牛黄丸制剂治疗缺血性中风急性期随机对照试验的系统评价. 陕西中医, 2006, 27(7): 804~807. |
208. | 李可建. 脉络宁注射液治疗缺血性中风急性期随机对照试验的系统评价. 中华中医药杂志, 2006, 21(8): 471~474. |
209. | 李可建. 通心络胶囊治疗缺血性卒中急性期随机对照试验的Meta分析. 医药导报, 2006, 25(9): 893~896. |
210. | 李可建. 蚓激酶胶囊治疗缺血性中风急性期随机对照试验的系统评价. 中医研究, 2006, 19(9): 24~28. |
211. | 李可建. 川芎嗪注射液治疗缺血性中风急性期随机对照实验的系统评价. 时珍国医国药, 2006, 17(10): 1874~1876. |
212. | 李可建. 对脑心通胶囊治疗缺血性中风急性期随机对照研究的系统评价. 山东医药, 2006, 46(14): 35~37. |
213. | 李可建. 水蛭治疗缺血性中风急性期随机对照试验的系统评价. 现代中西医结合杂志, 2006, 15(17): 2311~2312, 2314. |
214. | 李可建. 补阳还五汤治疗缺血性中风急性期随机对照试验的系统评价研究. 云南中医学院学报, 2006, 29(6): 24~28. |
215. | 李可建. 刺五加注射液治疗缺血性中风急性期随机对照试验的系统评价. 中成药, 2006, 28(10): 1458~1461. |
216. | 李可建. 丹参制剂治疗缺血性中风急性期随机对照试验的系统评价. 中医药学刊, 2006, 24(9): 1640~1642. |
217. | 李可建. 补阳还五汤治疗出血性中风急性期随机对照试验的系统评价. 贵阳中医学院学报, 2006, 28(6): 11~13. |
218. | 李可建. 银杏叶制剂治疗缺血性中风急性期随机对照试验的系统评价. 中医药导报, 2006, 12(11): 1~5. |
219. | 李可建. 补阳还五汤治疗不同类型中风疗效的系统评价研究. 天津中医药, 2006, 23(5): 372~376. |
220. | 李可建, 马丽虹. 脉络宁注射液治疗缺血性中风急性期随机对照试验的Meta-分析. 中国中医基础医学杂志, 2006, 12(11): 865~867. |
221. | 马丽虹, 李茂峰, 李可建, 等. 红花注射液治疗缺血性中风急性期随机对照试验的系统评价. 山东中医杂志, 2006, 25(9): 590~593. |
222. | 李可建, 马丽虹. 蝮蛇抗栓酶治疗缺血性中风急性期随机对照试验的系统评价. 中医药学刊, 2006, 24(4): 622~625. |
223. | 李可建, 迟华基. 生脉注射液治疗缺血性中风急性期随机对照试验的系统评价. 辽宁中医杂志, 2006, 33(8): 936~937. |
224. | 李可建. 补阳还五汤治疗原发性肾病综合征随机对照试验的系统评价研究. 辽宁中医药大学学报, 2006, 8(6): 63~64. |
225. | 张迎春, 智友朝, 谭秦湘, 等. 川芎嗪治疗不稳定性心绞痛疗效的系统评价. 中国临床康复, 2006, 10(27): 102~104. |
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